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      Dietary modifications for enhanced cancer therapy

      , ,
      Nature
      Springer Science and Business Media LLC

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          Abstract

          <p class="first" id="d16381136e135">Tumours depend on nutrients supplied by the host for their growth and survival. Modifications to the host's diet can change nutrient availability in the tumour microenvironment, which might represent a promising strategy for inhibiting tumour growth. Dietary modifications can limit tumour-specific nutritional requirements, alter certain nutrients that target the metabolic vulnerabilities of the tumour, or enhance the cytotoxicity of anti-cancer drugs. Recent reports have suggested that modification of several nutrients in the diet can alter the efficacy of cancer therapies, and some of the newest developments in this quickly expanding field are reviewed here. The results discussed indicate that the dietary habits and nutritional state of a patient must be taken into account during cancer research and therapy. </p>

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          Author and article information

          Journal
          Nature
          Nature
          Springer Science and Business Media LLC
          0028-0836
          1476-4687
          March 2020
          March 25 2020
          March 2020
          : 579
          : 7800
          : 507-517
          Article
          10.1038/s41586-020-2124-0
          32214253
          08ef5a8d-b6bc-4304-9d62-434aa72b250a
          © 2020

          http://www.springer.com/tdm

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