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      Computer Estimation of Stroke Volume from Aortic Pulse Contour in Dogs and Humans

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          Abstract

          Stroke volume (SV) estimation from computer analysis of aortic pressure contour was tested in 12 anesthetized dogs and 2 humans with A-V block. The ‘actual’ SV was calculated from right-heart bypass pump flow values in 6 open-chest dogs, from heart rate (HR) and cardiac output (CO) using dye dilution in 6 closed-chest dogs and by the Fick method in the human subjects. SV changes were induced by changes in pacing rate and pump flow, infusion and withdrawal of fluids and exercise. Mean arterial pressure was altered in dogs by changes in CO and infusions of drugs.In the dogs, the method (using Warner’s formula) proved consistent (r = 0.774, p < 0.001, S<sub>y. x</sub> = 3.82 ml) but inaccurate (slope = 0.386) in 627 comparisons. The same conclusions were reached in 11 human comparisons. The Kouchoukos formula showed similar problems. Corrections are suggested based on these results.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1974
          1974
          29 October 2008
          : 59
          : 6
          : 350-366
          Affiliations
          Department of Internal Medicine, University of Utah College of Medicine, and the Veterans Administration Hospital, Salt Lake City, Utah
          Article
          169694 Cardiology 1974;59:350–366
          10.1159/000169694
          4620069
          © 1974 S. Karger AG, Basel

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          Page count
          Pages: 17
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