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      Identification of staphylococcal Panton-Valentine leukocidin as a potent dermonecrotic toxin.

      Infection and Immunity

      pharmacology, immunology, Toxins, Biological, Staphylococcus aureus, pathology, Skin, Rabbits, Necrosis, Leukocidins, Intradermal Tests, Immunization, Immune Sera, Animals

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          Abstract

          The Panton-Valentine leukocidin of Staphylococcus aureus was shown to exhibit a potent dermonecrotic effect when injected intradermally into rabbits. This effect could be abrogated by immunizing animals with the F component or both components, but immunization with the S component appeared to exacerbate certain of the intradermal responses.

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          7399669
          550947

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