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      Safety of synthetic and biological DMARDs: a systematic literature review informing the 2019 update of the EULAR recommendations for the management of rheumatoid arthritis.

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          Abstract

          To perform a systematic literature review (SLR) concerning the safety of synthetic (s) and biological (b) disease-modifying anti rheumatic dugs (DMARDs) to inform the 2019 update of the EULAR recommendations for the management of rheumatoid arthritis (RA).

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          Author and article information

          Journal
          Ann. Rheum. Dis.
          Annals of the rheumatic diseases
          BMJ
          1468-2060
          0003-4967
          June 2020
          : 79
          : 6
          Affiliations
          [1 ] Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands alexsepriano@gmail.com.
          [2 ] NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal, Lisboa, Portugal.
          [3 ] Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria.
          [4 ] 2nd Department of Medicine, Hietzing Hospital, Vienna, Austria.
          [5 ] Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
          [6 ] Department of Rheumatology, Hôpital Cochin. Assistance Publique - Hôpitaux de Paris, Paris, France.
          [7 ] Clinical Epidemiology and Biostatistics, INSERM U1153, Paris, France.
          [8 ] Department Rheumatology and Clinical Immunology, Amsterdam University Medical Centres, Amsterdam, The Netherlands.
          [9 ] Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
          [10 ] Department of Rheumatology, University Medical Centre Utrecht, Utrecht, The Netherlands.
          [11 ] Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.
          [12 ] EULAR Standing Committee of People with Arthritis/Rheumatism in Europe, Zurich, Switzerland.
          [13 ] Center for Personalized Health, Feinstein Institute for Medical Research, Northwell Health, New York, New York, USA.
          [14 ] Amsterdam University Medical Center (ARC), Amsterdam, The Netherlands.
          [15 ] Department of Rheumatology, Zuyderland Medical Center, Heerlen, The Netherlands.
          Article
          annrheumdis-2019-216653
          10.1136/annrheumdis-2019-216653
          32033941
          0950e5b3-4d1c-4f79-96a1-181a9cbcd238
          History

          outcomes research,DMARDs (synthetic),anti-TNF,DMARDs (biologic),rheumatoid arthritis

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