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      Supervised Machine Learning based Ensemble Model for Accurate Prediction of Type 2 Diabetes

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          Abstract

          According to the American Diabetes Association(ADA), 30.3 million people in the United States have diabetes, but only 7.2 million may be undiagnosed and unaware of their condition. Type 2 diabetes is usually diagnosed for most patients later on in life whereas the less common Type 1 diabetes is diagnosed early on in life. People can live healthy and happy lives while living with diabetes, but early detection produces a better overall outcome on most patient's health. Thus, to test the accurate prediction of Type 2 diabetes, we use the patients' information from an electronic health records company called Practice Fusion, which has about 10,000 patient records from 2009 to 2012. This data contains individual key biometrics, including age, diastolic and systolic blood pressure, gender, height, and weight. We use this data on popular machine learning algorithms and for each algorithm, we evaluate the performance of every model based on their classification accuracy, precision, sensitivity, specificity/recall, negative predictive value, and F1 score. In our study, we find that all algorithms other than Naive Bayes suffered from very low precision. Hence, we take a step further and incorporate all the algorithms into a weighted average or soft voting ensemble model where each algorithm will count towards a majority vote towards the decision outcome of whether a patient has diabetes or not. The accuracy of the Ensemble model on Practice Fusion is 85\%, by far our ensemble approach is new in this space. We firmly believe that the weighted average ensemble model not only performed well in overall metrics but also helped to recover wrong predictions and aid in accurate prediction of Type 2 diabetes. Our accurate novel model can be used as an alert for the patients to seek medical evaluation in time.

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          Machine Learning Methods to Predict Diabetes Complications.

          One of the areas where Artificial Intelligence is having more impact is machine learning, which develops algorithms able to learn patterns and decision rules from data. Machine learning algorithms have been embedded into data mining pipelines, which can combine them with classical statistical strategies, to extract knowledge from data. Within the EU-funded MOSAIC project, a data mining pipeline has been used to derive a set of predictive models of type 2 diabetes mellitus (T2DM) complications based on electronic health record data of nearly one thousand patients. Such pipeline comprises clinical center profiling, predictive model targeting, predictive model construction and model validation. After having dealt with missing data by means of random forest (RF) and having applied suitable strategies to handle class imbalance, we have used Logistic Regression with stepwise feature selection to predict the onset of retinopathy, neuropathy, or nephropathy, at different time scenarios, at 3, 5, and 7 years from the first visit at the Hospital Center for Diabetes (not from the diagnosis). Considered variables are gender, age, time from diagnosis, body mass index (BMI), glycated hemoglobin (HbA1c), hypertension, and smoking habit. Final models, tailored in accordance with the complications, provided an accuracy up to 0.838. Different variables were selected for each complication and time scenario, leading to specialized models easy to translate to the clinical practice.
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            Prediction of Diabetes using Classification Algorithms

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              Genetic studies of the etiology of type 2 diabetes in Pima Indians: hunting for pieces to a complicated puzzle.

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                Author and article information

                Journal
                17 October 2019
                Article
                1910.09356
                096b70fd-b3cb-4086-be7f-7e5f39ba4d0d

                http://arxiv.org/licenses/nonexclusive-distrib/1.0/

                History
                Custom metadata
                9 Pages, # Tables and 8 Figures
                cs.LG stat.ML

                Machine learning,Artificial intelligence
                Machine learning, Artificial intelligence

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