Efficacy and tolerability of amlodipine camsylate/losartan 5/100-mg versus losartan/hydrochlorothiazide 100/12.5-mg fixed-dose combination in hypertensive patients nonresponsive to losartan 100-mg monotherapy.

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Abstract

The aim of this study was to determine whether the efficacy and tolerability of amlodipine camsylate/losartan 5/100 mg/d (AML/LOS) are noninferior to those of losartan/hydrochlorothiazide 100/12.5 mg/d (LOS/HCTZ) fixed-dose combination in hypertensive patients unresponsive to losartan 100-mg/d monotherapy.

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Author and article information

Journal

Journal ID (iso-abbrev): Clin Ther

Title: Clinical therapeutics

Publisher: Elsevier BV

ISSN (Electronic): 1879-114X

ISSN (Print): 0149-2918

Publication date (Electronic): Oct 01 2014

Volume: 36

Issue: 10

Affiliations

[1 ] Gachon University Gil Hospital, Incheon, Republic of Korea.

[2 ] Gachon University Gil Hospital, Incheon, Republic of Korea. Electronic address: encore@gilhospital.com.

[3 ] Konyang University Hospital, Daejeon, Republic of Korea.

[4 ] Korea University Anam Hospital, Seoul, Republic of Korea.

[5 ] Kwangju Christian Hospital, Kwangju, Republic of Korea.

[6 ] Dongguk University Ilsan Hospital, Ilsan, Republic of Korea.

[7 ] Soonchunhyang University Hospital, Seoul, Republic of Korea.

[8 ] Chungbuk National University Hospital, Jeonju, Republic of Korea.

[9 ] Hallym University Kangdong Sacred Heart Hospital, Seoul, Republic of Korea.

[10 ] VHS Medical Center, Seoul, Republic of Korea.

Article

Publisher Item ID: S0149-2918(14)00438-X

DOI: 10.1016/j.clinthera.2014.07.003

PubMed ID: 25146365

SO-VID: 0986e90c-42ed-46c7-911b-1e73703c7016

History

Keywords: losartan,amlodipine,hypertension

Data availability:

Keywords: losartan, amlodipine, hypertension

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