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One-step nucleic acid amplification for intraoperative detection of lymph node metastasis in breast cancer patients.
Masahiko Tsujimoto
1 ,
Kadzuki Nakabayashi ,
Katsuhide Yoshidome ,
Tomoyo Kaneko ,
Takuji Iwase ,
Futoshi Akiyama ,
Yo Kato ,
Hitoshi Tsuda ,
Shigeto Ueda ,
Kazuhiko Sato ,
Yasuhiro Tamaki ,
Shinzaburo Noguchi ,
Tatsuki R Kataoka ,
Hiromu Nakajima ,
Yoshifumi Komoike ,
Hideo Inaji ,
Koichiro Tsugawa ,
Koyu Suzuki ,
Seigo Nakamura ,
Motonari Daitoh ,
Yasuhiro Otomo ,
Nariaki Matsuura
Aug 15 2007
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Abstract
Detection of sentinel lymph node (SLN) metastasis in breast cancer patients has conventionally been determined by intraoperative histopathologic examination of frozen sections followed by definitive postoperative examination of permanent sections. The purpose of this study is to develop a more efficient method for intraoperative detection of lymph node metastasis.