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      Scaffolds and Cell-Based Tissue Engineering for Blood Vessel Therapy.

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          Abstract

          The increasing morbidity of cardiovascular diseases in modern society has made it crucial to develop a small-caliber blood vessel. In the absence of appropriate autologous vascular grafts, an alternative prosthesis must be constructed for cardiovascular disease patients. The aim of this article is to describe the advances in making cell-seeded cardiovascular prostheses. It also discusses the combinations of types of scaffolds and cells, especially autologous stem cells, which are suitable for application in tissue-engineered vessels with the favorable properties of mechanical strength, antithrombogenicity, biocompliance, anti-inflammation, fatigue resistance and long-term durability. This article highlights the advancements in cellular tissue-engineered vessels in recent years.

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          Author and article information

          Journal
          Cells Tissues Organs (Print)
          Cells, tissues, organs
          S. Karger AG
          1422-6421
          1422-6405
          2016
          : 202
          : 5-6
          27548610 000448169 10.1159/000448169

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