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      PRIME: A Programme to Reduce the Treatment Gap for Mental Disorders in Five Low- and Middle-Income Countries

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          Abstract

          Crick Lund and colleagues describe their plans for the PRogramme for Improving Mental health carE (PRIME), which aims to generate evidence on implementing and scaling up integrated packages of care for priority mental disorders in primary and maternal health care contexts in Ethiopia, India, Nepal, South Africa, and Uganda.

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          Global Burden of Disease and Risk Factors

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            Is Open Access

            Packages of Care for Mental, Neurological, and Substance Use Disorders in Low- and Middle-Income Countries: PLoS Medicine Series

            In a Perspective article, Vikram Patel and Graham Thornicroft introduce a new series in PLoS Medicine on mental health disorders in low- and middle-income countries that reviews the evidence for packages of care for ADHD, alcohol misuse disorders, dementia, depression, epilepsy, and schizophrenia.
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              Challenges in Developing Evidence-Based Recommendations Using the GRADE Approach: The Case of Mental, Neurological, and Substance Use Disorders

              Corrado Barbui and colleagues describe their use and adaptation of the GRADE approach in developing the guidelines for the WHO mental health Gap Action Programme (mhGAP).
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                Author and article information

                Journal
                PLoS Med
                PLoS Med
                PLoS
                plosmed
                PLoS Medicine
                Public Library of Science (San Francisco, USA )
                1549-1277
                1549-1676
                December 2012
                December 2012
                27 December 2012
                : 9
                : 12
                : e1001359
                Affiliations
                [1 ]University of Cape Town, Cape Town, South Africa
                [2 ]Stellenbosch University, Stellenbosch, South Africa
                [3 ]London School of Hygiene and Tropical Medicine, London, United Kingdom
                [4 ]Addis Ababa University, Addis Ababa, Ethiopia
                [5 ]Public Health Foundation of India, Hyderabad, India
                [6 ]HealthNet TPO, Kathmandu, Nepal
                [7 ]University of KwaZulu-Natal, Durban, South Africa
                [8 ]Human Sciences Research Council, Durban, South Africa
                [9 ]Makerere University, Kampala, Uganda
                [10 ]Institute of Psychiatry, King's College London, London, United Kingdom
                [11 ]University of Melbourne, Melbourne, Australia
                [12 ]London School of Economics and Political Science, London, United Kingdom
                [13 ]World Health Organization, Geneva, Switzerland
                [14 ]BasicNeeds, Bangalore, India
                [15 ]Sangath, Goa, India
                Author notes

                MT, MP, and VP are members of the PLOS Medicine Editorial Board. All other authors have declared that no competing interests exist.

                Conceived and designed the experiments: CL MT MS AF RS MJ IP AB FK MP GT CH RK DM SS DC SR SK SH LF VP. Analyzed the data: CL MT MS AF RS MJ IP AB FK MP GT CH RK DM SS DC SR SK SH LF VP. Wrote the first draft of the manuscript: CL MT VP. Contributed to the writing of the manuscript: CL MT MS AF RS MJ IP AB FK MP GT CH RK DM SS DC SR SK SH LF VP. ICMJE criteria for authorship read and met: CL MT MS AF RS MJ IP AB FK MP GT CH RK DM SS DC SR SK SH LF VP. Agree with manuscript results and conclusions: CL MT MS AF RS MJ IP AB FK MP GT CH RK DM SS DC SR SK SH LF VP.

                The Policy Forum allows health policy makers around the world to discuss challenges and opportunities for improving health care in their societies.

                Article
                PMEDICINE-D-12-01606
                10.1371/journal.pmed.1001359
                3531506
                23300387
                0a026c06-0250-456b-9776-13341b1527f3
                Copyright @ 2012

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                Page count
                Pages: 6
                Funding
                This document is an output from the PRIME Research Programme Consortium, funded by the UK Department of International Development (DFID) for the benefit of developing countries. SS and DC are staff members of the World Health Organization. GT is supported by a National Institute for Health Research (NIHR) Applied Programme grant, awarded to the South London and Maudsley NHS Foundation Trust. GT is also supported in relation to the NIHR Specialist Mental Health Biomedical Research Centre at the Institute of Psychiatry, King's College London and the South London and Maudsley NHS Foundation Trust. VP is supported by a Wellcome Trust Senior Research Fellowship. The authors alone are responsible for the views expressed in this publication and these views do not necessarily represent the decisions, policy or views of the World Health Organization or any of the funders. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Policy Forum
                Medicine
                Global Health
                Mental Health
                Primary Care
                Public Health

                Medicine
                Medicine

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