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      Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction.

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          Abstract

          Aldosterone blockade reduces mortality and morbidity among patients with severe heart failure. We conducted a double-blind, placebo-controlled study evaluating the effect of eplerenone, a selective aldosterone blocker, on morbidity and mortality among patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure.

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          Author and article information

          Journal
          N Engl J Med
          The New England journal of medicine
          Massachusetts Medical Society
          1533-4406
          0028-4793
          Apr 03 2003
          : 348
          : 14
          Affiliations
          [1 ] University of Michigan, Ann Arbor, USA. bpitt@umich.edu
          Article
          NEJMoa030207
          10.1056/NEJMoa030207
          12668699
          0aa5b155-2184-47de-ab05-4fe4bde142f5
          Copyright 2003 Massachusetts Medical Society
          History

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