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      Effect of Long-Wave Ultraviolet Light on the Lens

      Ophthalmic Research

      S. Karger AG

      Ultraviolet light, Human lens, Leucine transport, Leucine incorporation

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          A series of lens pairs (each pair from the same donor) from human eyebank eyes were incubated in a medium containing tracer leucine. One lens of each pair was exposed to long-wave ultraviolet light. The other was shielded. The irradiated lenses accumulated free leucine to a level only 53% of that in the shielded lenses. Irradiation depressed leucine incorporation to 29% of the control level. These results show that UV may adversely affect important parameters of human lens protein metabolism in vitro over a period of 10–30 h.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          04 December 2009
          : 15
          : 4
          : 216-219
          Emory University, Department of Ophthalmology, Atlanta, Ga., USA
          265262 Ophthalmic Res 1983;15:216–219
          © 1983 S. Karger AG, Basel

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          Pages: 4
          Original Paper


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