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      Scientific Achievements of John P. Peters

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          Abstract

          After the First World War in the United States, studies of water and electrolyte metabolism that were based in clinical departments were usually centered on patients with diseases which disrupted normal homeostatic functions. Renal abnormalities figured prominently, but liver disease, diabetes mellitus, various pituitary disorders, the edematous states and similar disorders – to the extent that they disturbed the volume or composition of the extracellular fluid – were also a fertile field of investigation. In general, the studies were confined to long-term observation of patients: there were few experimental manipulations and almost no animal work. The focus was a detailed analysis of the chemical composition of the blood and urine, and a relentless attempt to identify how these were disturbed under the impact of disease. The laboratory of Dr. John P. Peters at Yale typified this approach.

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          Author and article information

          Journal
          AJN
          Am J Nephrol
          10.1159/issn.0250-8095
          American Journal of Nephrology
          S. Karger AG
          978-3-8055-7424-2
          978-3-318-00852-4
          0250-8095
          1421-9670
          2002
          July 2002
          27 June 2002
          : 22
          : 2-3
          : 192-196
          Affiliations
          Departments of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Tex., USA
          Article
          63760 Am J Nephrol 2002;22:192–196
          10.1159/000063760
          12097739
          © 2002 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Figures: 1, Tables: 7, References: 13, Pages: 5
          Product
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/63760
          Categories
          Origins of Nephrology – The Modern Era

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