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      Anderson-Hynes pyeloplasty in children – long-term outcomes, how long follow up is necessary?

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          Abstract

          Introduction

          Pyeloplasty is commonly conducted in children with uretero-pelvic junction obstruction. Standard post-operational procedure involves only a short period of time after the surgery. What is the real number of complications, including those in the long-term? What is the function of the operated kidney?

          The aims of this study are to assess the effectiveness of pyeloplasty and to assess the suitability of conducting long term follow-up after pyeloplasty.

          Material and methods

          35 of 137 patients after open pyeloplasty between 1992–2006 responded to the invitation and returned for a control appointment. The median age was 8 years (range 1 month – 19 years). In 26 kidney units the disease proceeded with symptoms and in 10 cases it proceeded without symptoms. The predominant symptom was abdominal pain (n = 21). In each child both the control ultrasound and the diuretic renal scintigraphy of the kidneys were conducted.

          Results

          Regression of symptoms after the operation was obtained in 19 kidney units (73%). Improvement in scintigraphy was observed in 23 kidney units (82.1%), improvement in ultrasound was obtained in 32 (91%) kidney units. Complications which required surgical intervention occurred in 4 (11.1%) patients. One patient required operative removal of a pyelostomy tube, 2 patients (11.1%) required repeated pyleoplasty (23 and 27 months after the operation), one child required nephrectomy due to nephrogenic arterial hypertension (after 4 years).

          Conclusions

          Statistically, there are improvements of scintigraphic function of the kidney, improvements in ultrasound examinations, and the remission of symptoms after pyeoplasty. Most complications occur within 2 years after the surgery. Long-term follow up should be continued.

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          Most cited references19

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          Long-term success of antegrade endopyelotomy compared with pyeloplasty at a single institution.

          The classic standard for surgical repair of ureteropelvic junction (UPJ) obstruction has been open pyeloplasty, with a 95% success rate. Antegrade endopyelotomy is a less-invasive option with a slightly lower success rate. However, recent data call into question the long-term durability of UPJ repair. We present the long-term success of treatment of UPJ obstruction comparing these two modalities. We reviewed the medical records of patients undergoing percutaneous antegrade endopyelotomy or open and laparoscopic pyeloplasty for UPJ repair in our practice from 1988 to 2004. Success was defined as both radiographic and symptomatic improvement. We evaluated the impact of preoperative factors, including prior surgical repair, crossing vessels, renal function, and calculi, on success. The estimated 3-, 5-, and 10-year recurrence-free survival rates for the endopyelotomy group (N = 182) were 63%, 55%, and 41%, respectively, compared with 85%, 80%, and 75% for the pyeloplasty group (N = 175; P < 0.001). Of the failed endopyelotomies undergoing salvage open repair, 8 of 26 (31%) had crossing vessels. Poor renal function and previous failed pyeloplasty decreased success in the pyeloplasty group. Variation from standard cold-knife incision adversely affected endopyelotomy success. Long-term success rates after both endopyelotomy and pyeloplasty are worse than previously reported. Although most failures in both groups occurred within 2 years, failures continue to appear after 5 and 10 years, and patients should be followed accordingly. In view of these results of endopyelotomy, laparoscopic pyeloplasty may prove to be the preferred minimally invasive approach to repair UPJ obstruction.
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            Long-term followup of pediatric dismembered pyeloplasty: how long is long enough?

            We determined followup for pediatric patients after pyeloplasty based on the risk of late complications and the likelihood of return if discharged early from followup. We retrospectively reviewed the charts of all patients who underwent dismembered pyeloplasty at a single center between 1986 and 1996. Data regarding recurrent ureteropelvic junction obstruction and symptoms suggesting possibly recurrent obstruction were assessed. During the select period 123 pyeloplasties were performed. A total of 77 renal units were followed greater than 5 years. At 1 year postoperatively diuretic renograms showed normal drainage in 87% of the cases and prolonged or incomplete drainage in 13%. Obstruction recurred 8 years postoperatively in only 1 renal unit (0.8% overall, 1.3% of those followed greater than 5 years). Symptoms suggestive of recurrent obstruction developed in 18% of the patients but represented true recurrence in only 1. If one were to consider early followup discharge for these patients, the probability of repeat referral due to such symptoms was significantly higher in year 1 than in year 3. Most symptoms were initially assessed with ultrasound. Recurrent ureteropelvic junction obstruction is unlikely after unobstructed postoperative diuretic renogram and does not warrant long term followup. Ideal followup would extend to 2 years, covering the period when an initial symptom of recurrence is most likely to present and enabling baseline unobstructed renal ultrasound to be performed.
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              Neonatal management of unilateral hydronephrosis. Role for delayed intervention.

              R S Koff (1998)
              Hydronephrosis should be managed no differently in the newborn than in any other age group: UPJ obstruction should be surgically corrected as soon as the diagnosis is made. Unfortunately, the diagnosis of obstruction in the newborn with hydronephrosis is difficult and the traditional tests used in the older child or adult are not valid. Because newborn hydronephrosis is a relatively benign condition, surgical intervention should be delayed until the diagnosis of obstruction is proven. A protocol for evaluating the newborn with hydronephrosis is presented.
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                Author and article information

                Journal
                Cent European J Urol
                Cent European J Urol
                CEJU
                Central European Journal of Urology
                Polish Urological Association
                2080-4806
                2080-4873
                09 September 2017
                2017
                : 70
                : 4
                : 434-438
                Affiliations
                Department of Pediatric Surgery and Urology, Medical University of Wrocław, Wrocław, Poland
                Author notes
                Corresponding author Marcin Polok, Medical University of Wrocław, Department of Pediatric Surgery and Urology, 52, Curie-Skłodowskiej Street, 50-369 Wrocław, Poland. polok.m@ 123456gmail.com
                Article
                1431
                10.5173/ceju.2017.1431
                5791399
                0b277bf2-49fc-46c3-993d-88ac753ef817
                Copyright by Polish Urological Association

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

                History
                : 14 May 2017
                : 20 August 2017
                : 01 September 2017
                Categories
                Original Paper

                pyeloplasty,anderson-hynes,pediatric pyeloplasty,uretero-pelvic junction obstruction,long term follow up

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