An evaluation of the safety and efficacy of cariprazine in patients with acute exacerbation of schizophrenia: a phase II, randomized clinical trial.

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Abstract

Cariprazine is an orally active and potent D3 and D2 partial agonist with preferential binding to D3 receptors in development for the treatment of schizophrenia and bipolar mania. This study (NCT00694707) evaluated the efficacy and safety of cariprazine in patients with acute exacerbation of schizophrenia.

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Author and article information

Journal

Journal ID (iso-abbrev): Schizophr. Res.

Title: Schizophrenia research

Publisher: Elsevier BV

ISSN (Electronic): 1573-2509

ISSN (Print): 0920-9964

Publication date (Electronic): Feb 2014

Volume: 152

Issue: 2-3

Affiliations

[1 ] Forest Research Institute, Harborside Financial Center, Plaza V, Jersey City, NJ, USA. Electronic address: suresh.durgam@frx.com.

[2 ] Forest Research Institute, Harborside Financial Center, Plaza V, Jersey City, NJ, USA. Electronic address: anju.starace@frx.com.

[3 ] Forest Research Institute, Harborside Financial Center, Plaza V, Jersey City, NJ, USA. Electronic address: dayong.li@frx.com.

[4 ] Forest Research Institute, Harborside Financial Center, Plaza V, Jersey City, NJ, USA. Electronic address: raffaele.migliore@frx.com.

[5 ] Prescott Medical Communications Group, 205 N. Michigan Ave, Suite 3400, Chicago, IL, USA. Electronic address: aruth@prescottmed.com.

[6 ] Gedeon Richter Plc, H-1103 Budapest 10, Gyomroi u. 19-21, Hungary. Electronic address: gy.nemeth@richter.hu.

[7 ] Gedeon Richter Plc, H-1103 Budapest 10, Gyomroi u. 19-21, Hungary. Electronic address: i.laszlovszky@richter.hu.

Article

Publisher Item ID: S0920-9964(13)00658-0

DOI: 10.1016/j.schres.2013.11.041

PubMed ID: 24412468

SO-VID: 0b38b3f6-1d8d-4630-ab17-ed4941d8cf82

History

Keywords: Antipsychotic,Cariprazine,D(3),Dopamine,Schizophrenia

Data availability:

Keywords: Antipsychotic, Cariprazine, D(3), Dopamine, Schizophrenia

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