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      Early Exposure to Recommended Calorie Delivery in the Intensive Care Unit Is Associated With Increased Mortality in Patients With Acute Respiratory Distress Syndrome.

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          Abstract

          The Intensive Nutrition in Acute Lung Injury: Clinical Trial (INTACT), designed to evaluate outcomes of calorie delivery from acute respiratory distress syndrome (ARDS) diagnosis through hospital discharge, was stopped due to higher mortality in the intervention group. Post hoc analysis found timing and dose of calorie delivery influenced mortality. The objective of this retrospective cohort study was to determine if early vs late calorie exposure changed the hazard of death among a larger sample of patients with ARDS.

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          Author and article information

          Journal
          JPEN J Parenter Enteral Nutr
          JPEN. Journal of parenteral and enteral nutrition
          SAGE Publications
          1941-2444
          0148-6071
          May 2018
          : 42
          : 4
          Affiliations
          [1 ] Department of Food and Nutrition, Rush University Medical Center, Chicago, Illinois, USA.
          [2 ] Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
          [3 ] Department of Epidemiology and Biostatistics, University of Illinois at Chicago, Chicago, Illinois, USA.
          [4 ] Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA.
          Article
          10.1177/0148607117713483
          28662370
          0b447a1b-93c6-4eaa-b545-d1d366d9a34d
          History

          enteral nutrition,life cycle,adult,critical care,research and diseases,nutrition

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