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      • Record: found
      • Abstract: found
      • Article: found

      Electron Microscopic Observation on the Developing Rabbit and Human Vitreous Collagen Fibrils by Negative Staining

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          Abstract

          The vitreous fibrils of developing eyes of 3-day-old rabbits and 24th week human fetuses were examined by the negative staining method (phosphotungstic acid) electron microscopically. Fibrils about 10 nm in diameter and with no periodic striated pattern as well as adult ones were observed. Peculiar fibers were observed in both vitreous samples preserved at low temperature. Particularly, dimeric segment-long-spacing (SLS) aggregates and fibrous-long-spacing (FLS)-like aggregates were observed in 3-day-old rabbit vitreous. FLS-like aggregates showed a 125-nm light band and 50-nm dark band periodic pattern and seemed to be formed with 300-nm overlapping of dimeric SLS aggregates. The present results indicate that the developing vitreous could possibly form various types of collagen fiber under native conditions.

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1984
          Publication date (Print): 1984
          Publication date (Electronic): 04 December 2009
          Volume: 16
          Issue: 5
          Pages: 233-238
          Affiliations
          aDepartment of Ophthalmology, School of Medicine, and bElectron Microscopic Laboratory, Keio University, Tokyo, Japan
          Article
          Publisher ID: 265323 Other ID: Ophthalmic Res 1984;16:233–238
          DOI: 10.1159/000265323
          PubMed ID: 6207475
          SO-VID: 0b4f5aaf-ba4d-4eeb-b990-360c79281194
          Copyright © © 1984 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 26 September 1983
          Date accepted : 08 November 1983
          Page count
          Pages: 6
          Categories
          Subject: Original Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Dimeric segment-long-spacing (SLS),Type II collagen,Vitreous collagen,Fibrous type segment-long-spacing (SLS)
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Dimeric segment-long-spacing (SLS), Type II collagen, Vitreous collagen, Fibrous type segment-long-spacing (SLS)

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