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      Primary renal lymphoma: An incidental finding in an elderly male

      case-report

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Primary renal lymphoma (PRL) is a rare disease process which represents less than 1% of all renal masses and is an uncommon type of Non-Hodgkin's Lymphoma. PRL is of clinical significance due to the fact that unlike the more commonly seen renal cell carcinoma, PRL is treated with neoadjuvant chemotherapy followed by nephrectomy. This challenges the long held notion that preoperative biopsies are not necessary prior to nephrectomy for renal masses. In this paper, we present a case of a primary renal lymphoma and discuss its clinical significance.

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          Primary renal lymphoma does exist: case report and review of the literature.

          G Stallone, B Infante, C Manno … (2015)
          Primary renal lymphoma (PRL) is a controversial and rare disease and there is still no agreement on its existence. Many cases have been reported in the literature, but clear diagnostic criteria have not yet been established. Most of the reported cases are questionable because of incomplete staging or the presence of extrarenal disease. Here we report a new case and a review of the literature based on a critical examination of the diagnostic procedure. Thus, probably only 29 cases, ours included, should be recognized as PRL, because only these cases fulfil the three diagnostic criteria and underwent complete diagnostic screening, including renal biopsy, bone marrow biopsy and thoraco-abdominal computerised tomography (CT).
          Article 0 comments Cited 19 times – based on 0 reviews     Review now
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            An unusual case of bilateral renal enlargement due to primary renal lymphoma

            S C Dash, Shrirang K Purohit, S Mohanty … (2011)
            Primary renal lymphoma is an uncommon variant of extranodal non-Hodgkin’s lymphoma. Manifestations are usually nonspecific hematuria, fever, flank pain, and renal insufficiency. Pathological data are scanty; few reports indicate it has a very poor prognosis. We describe a child with bilateral symmetrically palpable kidneys, low-grade pyrexia, and arthralgia. Clinically, diagnosis was missed partly due to the fact that bilateral large renal tumors commonly produce asymmetric renal swelling, renal dysfunction, and hematuria which were absent in this case and partly due to rarity of the condition. However, radiological investigations combined with renal histology helped in establishing diagnosis in the present case.
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              Acute kidney injury secondary to renal large B-cell lymphoma: role of early renal biopsy.

              A. Shaaban, Suhail Al-Saleh, Samra Abouchacra … (2011)
              Renal involvement in large B-cell lymphoma represents an exceptional manifestation of non-Hodgkin lymphomas. Acute kidney injury (AKI) by lymphomatous infiltration is extremely rare and so far only 19 cases have been reported in the literature. We report a 67-year-old woman who presented with AKI and was found to have large B-cell lymphoma infiltrating her kidneys. The patient was treated with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) with rituximab, and a dramatic improvement of renal function was noticed after two weeks of treatment. Her renal function completely recovered after four weeks of treatment. In conclusion, lymphomatous infiltration of kidneys can directly lead to AKI. Rapid diagnosis and treatment is essential to preserve the renal function. Renal biopsy is the gold standard for the early diagnosis of non-Hodgkin lymphoma as a cause of AKI.
              Article 0 comments Cited 10 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Alexandra S. Vagasi
                Journal
                Journal ID (nlm-ta): Urol Case Rep
                Journal ID (iso-abbrev): Urol Case Rep
                Title: Urology Case Reports
                Publisher: Elsevier
                ISSN (Electronic): 2214-4420
                Publication date PMC-release: 10 July 2019
                Publication date Collection: September 2019
                Publication date (Electronic): 10 July 2019
                Volume: 26
                Electronic Location Identifier: 100965
                Affiliations
                [a ]New York Institute of Technology College of Osteopathic Medicine, 101 Northern Blvd, Glen Head, NY, 11545, USA
                [b ]The Icahn School of Medicine at Mount Sinai (South Nassau), One Healthy Way, Oceanside, NY, 11572, USA
                [c ]Mercy Medical Center, 1000 N Village Ave, Rockville Centre, NY, 11570, USA
                Author notes
                [∗ ]Corresponding author. South Nassau Communities Hospital, One Healthy Way, Oceanside, NY, 11572, USA. alexandra.vagasi@ 123456snch.org alexandra.vagasi@ 123456mssm.edu
                [1]

                Both authors contributed equally to this work.

                Article
                Publisher ID: S2214-4420(19)30240-2 Publisher ID: 100965
                DOI: 10.1016/j.eucr.2019.100965
                PMC ID: 6677884
                PubMed ID: 31388492
                SO-VID: 0bcf7322-bb7e-4649-95b3-8b20f4d24c0e
                Copyright © © 2019 Published by Elsevier Inc.
                License:

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                Date received : 25 June 2019
                Date accepted : 10 July 2019
                Categories
                Subject: Oncology

                Data availability:

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