Data on the effects of  Glochidion zeylanicum  leaf extracts in  Caenorhabditis elegans

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

The present article contains the data on the effects of Glochidion zeylanicum leaf extracts in C. elegans, which is related to the article " Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways" Chatrawee et al., 2019. This dataset was generated to better understand the antioxidant and anti-aging properties of G. zeylanicum leaf extracts in C. elegans. The bioactive compounds of the extracts were analyzed using GLC-MS, LC-MS, and RP-HPLC. The antioxidant properties were determined using phenolics, flavonoids, ABTS and DPPH assays. The in vivo antioxidant properties were performed using the intracellular ROS accumulation and the survival rate under oxidative stress condition assays. The brood size, body length and life-span were determined regarding anti-aging properties in this data.

Related collections

Most cited references 2

Record: found
Abstract: found
Article: not found

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

D Ayusawa, S Yanase, N Matsuda … (1998)

Much attention has focused on the aetiology of oxidative damage in cellular and organismal ageing. Especially toxic are the reactive oxygen byproducts of respiration and other biological processes. A mev-1(kn1) mutant of Caenorhabditis elegans has been found to be hypersensitive to raised oxygen concentrations. Unlike the wild type, its lifespan decreases dramatically as oxygen concentrations are increased from 1 to 60%. Strains bearing this mutation accumulate markers of ageing (such as fluorescent materials and protein carbonyls) faster than the wild type. We show here that mev-1 encodes a subunit of the enzyme succinate dehydrogenase cytochrome b, which is a component of complex II of the mitochondrial electron transport chain. We found that the ability of complex II to catalyse electron transport from succinate to ubiquinone is compromised in mev-1 animals. This may cause an indirect increase in superoxide levels, which in turn leads to oxygen hypersensitivity and premature ageing. Our results indicate that mev-1 governs the rate of ageing by modulating the cellular response to oxidative stress.

0 comments Cited 121 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: not found
Article: not found

Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways

Chatrawee Duangjan, Panthakarn Rangsinth, Xiaojie Gu … (2019)

0 comments Cited 22 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Contributors

Michael Wink

Tewin Tencomnao

Journal

Journal ID (nlm-ta): Data Brief

Journal ID (iso-abbrev): Data Brief

Title: Data in Brief

Publisher: Elsevier

ISSN (Electronic): 2352-3409

Publication date PMC-release: 31 August 2019

Publication date Collection: October 2019

Publication date (Electronic): 31 August 2019

Volume: 26

Electronic Location Identifier: 104461

Affiliations

[a ]Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand

[b ]Department of Biotechnology, School of Environmental and Chemical Engineering, Dalian Jiaotong University, Dalian, 116028, China

[c ]College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou, 350002, China

[d ]Institute of Pharmacy and Molecular Biotechnology, Im Neuenheimer Feld 364, Heidelberg University, 69120, Heidelberg, Germany

[e ]Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand

Author notes

[∗ ]Corresponding author. Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand. tewin.t@ 123456chula.ac.th

[∗∗ ]Corresponding author. Wink@ 123456uni-heidelberg.de

Article

Publisher ID: S2352-3409(19)30816-9 Publisher ID: 104461

DOI: 10.1016/j.dib.2019.104461

PMC ID: 6804397

SO-VID: 0c1d53c7-45cb-42f2-9038-065bdf1e248b

License:

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

History

Date received : 1 August 2019

Date revision received : 21 August 2019

Date accepted : 23 August 2019

Comments

Comment on this article

scite_

Cited by 1

Vitis Vinifera Leaf Extract Protects Against Glutamate-Induced Oxidative Toxicity in HT22 Hippocampal Neuronal Cells and Increases Stress Resistance Properties in Caenorhabditis Elegans
Authors: Chatrawee Duangjan, Panthakarn Rangsinth, Shaoxiong Zhang …

See all cited by

Most referenced authors 21

See all reference authors

- Version 1

Data on the effects of Glochidion zeylanicum leaf extracts in Caenorhabditis elegans

Read this article at