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      Anthropometry Underestimates Body Protein Depletion in Haemodialysis Patients

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          Abstract

          The body composition of 62 haemodialysis patients (41 males) and 63 controls (30 males) was assessed using anthropometry and in vivo neutron activation analysis of body nitrogen. There was no significant difference between patients and controls in body mass index (BMI) and percentage body fat. Arm muscle circumference was significantly reduced in males. Lean body mass was strongly correlated with body nitrogen in controls (r = 0,951) but less so in patients (r = 0,876). The mean standardised body nitrogen index (NI) was reduced in male patients by 13% (95% confidence interval -9 to -17%) and in females by 4% (95% confidence interval + 4 to -12%). Of the 16 patients with a NI below the control range, arm muscle circumference was below the control range in only 3 and BMI less than 18 kg/m<sup>2</sup> in 2. NI was correlated negatively with the duration of renal replacement therapy, duration of haemodialysis, the number of previous failed transplants and the total dose of steroids received but not with current energy or protein intakes. Steroid dose was the only significant independent variable. Anthropometry underestimates body protein depletion in haemodialysis patients and the degree of protein loss is related to the cumulative dose of corticosteroids previously received.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1991
          1991
          11 December 2008
          : 59
          : 1
          : 33-40
          Affiliations
          Departments of aNephrology, bMedical Physics, cDietetics, and dClinical Nutrition and Metabolism, Monash Medical Centre, Prince Henry’s Campus, and eDepartment of Medicine, Monash University, Melbourne, Victoria, Australia
          Article
          186514 Nephron 1991;59:33–40
          10.1159/000186514
          1944745
          © 1991 S. Karger AG, Basel

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          Page count
          Pages: 8
          Categories
          Original Paper

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