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      Melatonin and jet lag: Confirmatory result using a simplified protocol

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      Biological Psychiatry

      Elsevier BV

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          Abstract

          This study replicates the alleviation of jet-lag with melatonin in a simplified protocol for eastward flight. At 22-n hr (n is the time-lag between the North American departure point and France), subjects took either melatonin (8 mg, n = 15), or placebo (n = 15) on the day of the return flight and for 3 consecutive days. On day 8, self-ratings significantly discriminated between melatonin and placebo for global treatment efficacy, morning fatigue, and evening sleepiness.

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          Author and article information

          Journal
          Biological Psychiatry
          Biological Psychiatry
          Elsevier BV
          00063223
          October 1992
          October 1992
          : 32
          : 8
          : 705-711
          Article
          10.1016/0006-3223(92)90300-O
          1457626
          © 1992

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