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      Serial Magnetic Resonance Imaging of Global and Regional Left Ventricular Remodeling during 1 Year after Acute Myocardial Infarction


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          Biplane long-axis cine MRI was performed in 51 patients 1, 13, 26, and 52 weeks after their first AMI. LV mass index (LVMI) was significantly increased 1 week after AMI (84.3 ± 16.9 vs. 68.1 ± 11.4 g/m<sup>2</sup> controls, n = 48, p < 0.001), presumably owing to edema of the infarcted myocardium. Six months after AMI, LVMI decreased to 76.5 ± 16.4 g/m<sup>2</sup>, but had again augmented after 1 year (81.8 ± 17.3 g/m<sup>2</sup>, p < 0.05), suggesting late, compensatory left ventricular hypertrophy. In patients treated with primary percutaneous transluminal coronary angioplasty, LVMI decreased 5% over 1 year, while LVMI increased 10% in patients receiving thrombolysis (p < 0.05). In the entire population, the global increase in LVMI 1 year after AMI seemed to reflect global cavity dilatation with unchanged thickness of the vital myocardium. In conclusion, in patients receiving contemporary treatment, LV remodeling only partially complied with the classical patho-anatomical concept.

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          Percutaneous Transluminal Coronary Angioplasty versus Thrombolysis in Acute Myocardial Infarction: A Prospective, Matched, Controlled Study


            Author and article information

            S. Karger AG
            December 2001
            10 December 2001
            : 96
            : 2
            : 106-114
            Departments of aCardiology and bCardiothoracic and Vascular Surgery, cCentre of Magnetic Resonance, Institute of Experimental Clinical Research, Aarhus University Hospital, Aarhus, Denmark
            49092 Cardiology 2001;96:106–114
            © 2001 S. Karger AG, Basel

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            Page count
            Figures: 3, Tables: 2, References: 32, Pages: 9
            Noninvasive and Diagnostic Cardiology


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