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      Breastfeeding May Protect from Developing Attention-Deficit/Hyperactivity Disorder

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          Abstract

          Breastfeeding has a positive influence on physical and mental development. Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral disorder with major social, familial, and academic influences. The present study aimed to evaluate whether ADHD is associated with a shorter duration of breastfeeding. In this retrospective matched study, children 6-12 years old diagnosed at Schneider's Children Medical Center (Petach Tikva, Israel) with ADHD between 2008 and 2009 were compared with two control groups. The first one consisted of healthy (no ADHD) siblings of ADHD children; the second control group consisted of children without ADHD who consulted at the otolaryngology clinic. A constructed questionnaire about demographic, medical, and perinatal findings, feeding history during the first year of life, and a validated adult ADHD screening questionnaire were given to both parents of every child in each group. In children later diagnosed as having ADHD, 43% were breastfed at 3 months of age compared with 69% in the siblings group and 73% in the control non-related group (p=0.002). By 6 months of age 29% of ADHD children were breastfed compared with 50% in the siblings group and 57% in the control non-related group (p=0.011). A stepwise logistic regression that included the variables found to be significant in univariate analysis demonstrated a significant association between ADHD and lack of breastfeeding at 3 months of age, maternal age at birth, male gender, and parental divorce. Children with ADHD were less likely to breastfeed at 3 months and 6 months of age than children in the two control groups. We speculate that breastfeeding may have a protective effect from developing ADHD later in childhood.

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          Most cited references15

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          Attention-deficit hyperactivity disorder.

          Attention-deficit hyperactivity disorder (ADHD) is a disorder of inattention, impulsivity, and hyperactivity that affects 8-12% of children worldwide. Although the rate of ADHD falls with age, at least half of children with the disorder will have impairing symptoms in adulthood. Twin, adoption, and molecular genetic studies show ADHD to be highly heritable, and other findings have recorded obstetric complications and psychosocial adversity as predisposing risk factors. Converging evidence from animal and human studies implicates the dysregulation of frontal-subcortical-cerebellar catecholaminergic circuits in the pathophysiology of ADHD, and molecular imaging studies suggest that abnormalities of the dopamine transporter lead to impaired neurotransmission. Studies during the past decade have shown the safety and effectiveness of new non-stimulant drugs and long-acting formulations of methylphenidate and amfetamine. Other investigations have also clarified the appropriate role of targeted psychosocial treatments in the context of ongoing pharmacotherapy.
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            Externalizing behavior problems and academic underachievement in childhood and adolescence: Causal relationships and underlying mechanisms.

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              Attention deficit disorder: a review of the past 10 years.

              C Cantwell (1996)
              To summarize knowledge about attention deficit disorder in the areas of epidemiology, etiology, clinical predictors, assessments, natural history and outcome, and management. A literature review of articles, books, and chapters primarily published in the past 10 years was completed. Articles presenting new information, most relevant to clinical practice, were reviewed. Key findings in the areas listed above are presented. Major advances have been made in all areas. The clinical picture has been refined and developmental manifestations have been delineated. Patterns of comorbidity have been detailed. Various etiological factors, particularly in the biological area, have been investigated. Multimodal management has been promulgated as the treatment of choice.
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                Author and article information

                Journal
                Breastfeeding Medicine
                Breastfeeding Medicine
                Mary Ann Liebert Inc
                1556-8253
                1556-8342
                August 2013
                August 2013
                : 8
                : 4
                : 363-367
                Affiliations
                [1 ]Pediatric Neurology and Developmental Unit, Loewenstein Rehabilitation Hospital, Raanana, Israel.
                [2 ]Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
                [3 ]Department of Neonatology, Rabin Medical Center, Petach Tikva, Israel.
                [4 ]Dana Dwek Children's Hospital, Tel Aviv, Israel.
                [5 ]Pediatric Neurology Unit, Schneider Children's Medical Center, Petach Tikva, Israel.
                [6 ]Pediatric Otolaryngology Unit, Schneider Children's Medical Center, Petach Tikva, Israel.
                Article
                10.1089/bfm.2012.0145
                23560473
                0ca19660-0b12-47cc-832f-1da6bb0f3ee9
                © 2013
                History

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