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      Tracing the mobility of a Late Epigravettian (~ 13 ka) male infant from Grotte di Pradis (Northeastern Italian Prealps) at high-temporal resolution

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          Abstract

          We present the results of a multi-disciplinary investigation on a deciduous human tooth (Pradis 1), recently recovered from the Epigravettian layers of the Grotte di Pradis archaeological site (Northeastern Italian Prealps). Pradis 1 is an exfoliated deciduous molar (Rdm 2), lost during life by an 11–12-year-old child. A direct radiocarbon date provided an age of 13,088–12,897 cal BP (95% probability, IntCal20). Amelogenin peptides extracted from tooth enamel and analysed through LC–MS/MS indicate that Pradis 1 likely belonged to a male. Time-resolved 87Sr/ 86Sr analyses by laser ablation mass spectrometry (LA-MC-ICPMS), combined with dental histology, were able to resolve his movements during the first year of life (i.e. the enamel mineralization interval). Specifically, the Sr isotope ratio of the tooth enamel differs from the local baseline value, suggesting that the child likely spent his first year of life far from Grotte di Pradis. Sr isotopes are also suggestive of a cyclical/seasonal mobility pattern exploited by the Epigravettian human group. The exploitation of Grotte di Pradis on a seasonal, i.e. summer, basis is also indicated by the faunal spectra. Indeed, the nearly 100% occurrence of marmot remains in the entire archaeozoological collection indicates the use of Pradis as a specialized marmot hunting or butchering site. This work represents the first direct assessment of sub-annual movements observed in an Epigravettian hunter-gatherer group from Northern Italy.

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          The PRIDE database and related tools and resources in 2019: improving support for quantification data

          Abstract The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world’s largest data repository of mass spectrometry-based proteomics data, and is one of the founding members of the global ProteomeXchange (PX) consortium. In this manuscript, we summarize the developments in PRIDE resources and related tools since the previous update manuscript was published in Nucleic Acids Research in 2016. In the last 3 years, public data sharing through PRIDE (as part of PX) has definitely become the norm in the field. In parallel, data re-use of public proteomics data has increased enormously, with multiple applications. We first describe the new architecture of PRIDE Archive, the archival component of PRIDE. PRIDE Archive and the related data submission framework have been further developed to support the increase in submitted data volumes and additional data types. A new scalable and fault tolerant storage backend, Application Programming Interface and web interface have been implemented, as a part of an ongoing process. Additionally, we emphasize the improved support for quantitative proteomics data through the mzTab format. At last, we outline key statistics on the current data contents and volume of downloads, and how PRIDE data are starting to be disseminated to added-value resources including Ensembl, UniProt and Expression Atlas.
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            THE INTCAL20 NORTHERN HEMISPHERE RADIOCARBON AGE CALIBRATION CURVE (0–55 CAL kBP)

            Radiocarbon ( 14 C) ages cannot provide absolutely dated chronologies for archaeological or paleoenvironmental studies directly but must be converted to calendar age equivalents using a calibration curve compensating for fluctuations in atmospheric 14 C concentration. Although calibration curves are constructed from independently dated archives, they invariably require revision as new data become available and our understanding of the Earth system improves. In this volume the international 14 C calibration curves for both the Northern and Southern Hemispheres, as well as for the ocean surface layer, have been updated to include a wealth of new data and extended to 55,000 cal BP. Based on tree rings, IntCal20 now extends as a fully atmospheric record to ca. 13,900 cal BP. For the older part of the timescale, IntCal20 comprises statistically integrated evidence from floating tree-ring chronologies, lacustrine and marine sediments, speleothems, and corals. We utilized improved evaluation of the timescales and location variable 14 C offsets from the atmosphere (reservoir age, dead carbon fraction) for each dataset. New statistical methods have refined the structure of the calibration curves while maintaining a robust treatment of uncertainties in the 14 C ages, the calendar ages and other corrections. The inclusion of modeled marine reservoir ages derived from a three-dimensional ocean circulation model has allowed us to apply more appropriate reservoir corrections to the marine 14 C data rather than the previous use of constant regional offsets from the atmosphere. Here we provide an overview of the new and revised datasets and the associated methods used for the construction of the IntCal20 curve and explore potential regional offsets for tree-ring data. We discuss the main differences with respect to the previous calibration curve, IntCal13, and some of the implications for archaeology and geosciences ranging from the recent past to the time of the extinction of the Neanderthals.
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              Bayesian Analysis of Radiocarbon Dates

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                Author and article information

                Contributors
                federico.lugli6@unibo.it
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                16 May 2022
                16 May 2022
                2022
                : 12
                : 8104
                Affiliations
                [1 ]GRID grid.6292.f, ISNI 0000 0004 1757 1758, Department of Cultural Heritage, , University of Bologna, ; Ravenna, Italy
                [2 ]GRID grid.7548.e, ISNI 0000000121697570, Department of Chemical and Geological Sciences, , University of Modena and Reggio Emilia, ; Modena, Italy
                [3 ]GRID grid.9759.2, ISNI 0000 0001 2232 2818, Human Osteology Lab, School of Anthropology and Conservation, , University of Kent, ; Canterbury, UK
                [4 ]GRID grid.6292.f, ISNI 0000 0004 1757 1758, Department of Biological, Geological and Environmental Sciences, , University of Bologna, ; Bologna, Italy
                [5 ]GRID grid.4711.3, ISNI 0000 0001 2183 4846, HUMANE - Human Ecology and Archaeology, Dept. Archaeology and Anthropology, , Institució Milà i Fontanals de Investigación en Humanidades, Consejo Superior de Investigaciones Cientificas (IMF - CSIC), ; Barcelona, Spain
                [6 ]GRID grid.436694.a, ISNI 0000 0001 2154 5833, MUSE, Museum of Science, ; Trento, Italy
                [7 ]GRID grid.8484.0, ISNI 0000 0004 1757 2064, Departement of Humanities, Section of Prehistoric and Anthropological Sciences, , University of Ferrara, ; Ferrara, Italy
                [8 ]GRID grid.5608.b, ISNI 0000 0004 1757 3470, Department of Cultural Heritage, , University of Padua, ; Padua, Italy
                [9 ]GRID grid.419518.0, ISNI 0000 0001 2159 1813, Department of Human Evolution, , Max Planck Institute for Evolutionary Anthropology, ; Leipzig, Germany
                [10 ]GRID grid.451388.3, ISNI 0000 0004 1795 1830, Ancient Genomics Lab, , The Francis Crick Institute, ; London, UK
                [11 ]GRID grid.6292.f, ISNI 0000 0004 1757 1758, Department of Chemistry “Giacomo Ciamician”, , University of Bologna, ; Bologna, Italy
                [12 ]GRID grid.498067.4, ISNI 0000 0001 0845 4216, CEREGE, Aix Marseille Université, CNRS, IRD, INRAE, Collège de France, Technopôle de L‘Arbois, ; Aix-en-Provence, France
                [13 ]GRID grid.5942.a, ISNI 0000 0004 1759 508X, Elettra - Sincrotrone Trieste S.C.P.A., ; Basovizza (Trieste), Italy
                [14 ]LINXS – Lund Institute for advanced Neutron and X-ray Science, Lund, Sweden
                [15 ]GRID grid.7839.5, ISNI 0000 0004 1936 9721, Frankfurt Isotope and Element Research Center (FIERCE), , Goethe-Universität Frankfurt, ; Frankfurt am Main, Germany
                [16 ]GRID grid.7839.5, ISNI 0000 0004 1936 9721, Institut Für Geowissenschaften, , Goethe-Universität Frankfurt, ; Frankfurt am Main, Germany
                [17 ]Pradis Cave Museum, Clauzetto, Italy
                Article
                12193
                10.1038/s41598-022-12193-6
                9110381
                35577834
                0cb8de3a-5103-47fe-91a7-e59809c765f6
                © The Author(s) 2022

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 23 December 2021
                : 20 April 2022
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/100010663, H2020 European Research Council;
                Award ID: 724046
                Award ID: 803147
                Award Recipient :
                Funded by: FundRef http://dx.doi.org/10.13039/100010665, H2020 Marie Skłodowska-Curie Actions;
                Award ID: 842812
                Award Recipient :
                Funded by: FundRef http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
                Award ID: 161/923-1
                Award Recipient :
                Funded by: FundRef http://dx.doi.org/10.13039/501100011618, Wilhelm und Else Heraeus-Stiftung;
                Award ID: 161/921-1
                Award Recipient :
                Funded by: FundRef http://dx.doi.org/10.13039/501100003407, Ministero dell’Istruzione, dell’Università e della Ricerca;
                Award ID: SAPIENS
                Award Recipient :
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                © The Author(s) 2022

                Uncategorized
                anthropology,archaeology,biogeochemistry
                Uncategorized
                anthropology, archaeology, biogeochemistry

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