Effect of reversal of neuromuscular blockade with sugammadex versus usual care on bleeding risk in a randomized study of surgical patients.

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Abstract

Previous studies show a prolongation of activated partial thromboplastin time and prothrombin time in healthy volunteers after treatment with sugammadex. The authors investigated the effect of sugammadex on postsurgical bleeding and coagulation variables.

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Journal

Journal ID (iso-abbrev): Anesthesiology

Title: Anesthesiology

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1528-1175

ISSN (Print): 0003-3022

Publication date (Electronic): Nov 2014

Volume: 121

Issue: 5

Affiliations

[1 ] From the Department for Anaesthesiology and Critical Care Medicine, Franziskus Hospital Bielefeld and Hannover Medical School, Hannover, Germany (N.R.-M.); Biostatistics, MSD-Oss, Oss, The Netherlands (H.F., M.S.); Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, and Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (S.S.); Anesthesiology and Intensive Care, Medical Research Society, Danube Hospital, Vienna, Austria (W.K.); Department of Anesthesia and Intensive Care, Annastift, Hannover, Germany (M.P.); Klinik für Anästhesiologie der Technischen Universität München, Munich, Germany (M.B.); Klinik für Anästhesie und Intensivtherapie, Universitätsklinikum, Marburg, Germany (H.W.); Global Scientific and Medical Publications, Merck & Co., Inc., Whitehouse Station, New Jersey (C.M.S.); and Clinical Research, Merck & Co., Inc., Whitehouse Station, New Jersey (D.W.-H., T.W., A.S.).

Article

DOI: 10.1097/ALN.0000000000000424

PubMed ID: 25208233

SO-VID: 0d198275-2f95-4357-8fdd-84888ca65a40

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