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      Effect of reversal of neuromuscular blockade with sugammadex versus usual care on bleeding risk in a randomized study of surgical patients.

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          Abstract

          Previous studies show a prolongation of activated partial thromboplastin time and prothrombin time in healthy volunteers after treatment with sugammadex. The authors investigated the effect of sugammadex on postsurgical bleeding and coagulation variables.

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          Author and article information

          Journal
          Anesthesiology
          Anesthesiology
          Ovid Technologies (Wolters Kluwer Health)
          1528-1175
          0003-3022
          Nov 2014
          : 121
          : 5
          Affiliations
          [1 ] From the Department for Anaesthesiology and Critical Care Medicine, Franziskus Hospital Bielefeld and Hannover Medical School, Hannover, Germany (N.R.-M.); Biostatistics, MSD-Oss, Oss, The Netherlands (H.F., M.S.); Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, and Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (S.S.); Anesthesiology and Intensive Care, Medical Research Society, Danube Hospital, Vienna, Austria (W.K.); Department of Anesthesia and Intensive Care, Annastift, Hannover, Germany (M.P.); Klinik für Anästhesiologie der Technischen Universität München, Munich, Germany (M.B.); Klinik für Anästhesie und Intensivtherapie, Universitätsklinikum, Marburg, Germany (H.W.); Global Scientific and Medical Publications, Merck & Co., Inc., Whitehouse Station, New Jersey (C.M.S.); and Clinical Research, Merck & Co., Inc., Whitehouse Station, New Jersey (D.W.-H., T.W., A.S.).
          Article
          10.1097/ALN.0000000000000424
          25208233

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