8
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Síndrome do seio cavernoso: estudo de 70 casos Translated title: Cavernous sinus syndrome: study of 70 cases

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          RESUMO Objetivo: Caracterizar as manifestações clínicas e determinar a distribuição epidemiológica e etiológica da síndrome do seio cavernoso (SSC) pela primeira vez no Brasil. Métodos: Os casos de SSC vistos num período de 15 anos foram analisados. Os pacientes foram submetidos a completo exame neurológico e oftalmológico, a extensa propedéutica laboratorial e a exames de imagem do encéfalo para determinação da etiología. Em alguns pacientes foí realizada biópsia cerebral. Resultados: 70 casos foram encontrados com idades entre 4 e 74 anos (mediana de 41). Ambos sexos foram igualmente afetados. Cefaléia ocorreu em 80% dos pacientes, envolvimento do III nervo em 76%, do IV em 43%, do VI em 59%, e do nervo óptico em 46% dos casos. A síndrome de Tolosa-Hunt foí encontrada em 18 pacientes, a paquimeningite hipertrófica em 17, os tumores em 12, os aneurismas em 11, as fístulas carótido-cavernosas em 10, tuberculoma em um, e tromboflebite em uma paciente. Conclusões: XSSC ocorre em ambos os sexos e em todos os grupos etários, se manifestando por graves déficits neuro-oftalmológícos. Neuropatía óptica é comum. Inflamação foi a causa mais freqüentemente encontrada da SSC nesta série.

          Translated abstract

          SUMMARY Purpose: To determine the epidemiological and clinical features of the cavernous sinus syndrome as well as its most common etiologies in a series of patients in Brazil. Methods: The medical records of patients with cavernous sinus syndrome were analyzed. They had undergone an extensive laboratory workup including biopsy in selected cases. Results: 70 cases were found with ages ranging from 4 to?4 years (median 41). Both sexes were equally involved. Headache occurred in 80% of the patients; the III nerve was involved in 76%, the IV in 43%, the VI in 59%. Optic neuropathy was seen in 46%) of the cases. The main etiologies were: Tolosa-Hunt syndrome in 18 patients, hypertrophic pachymeningitis in 17, tumors in 12, aneurysms in 11; tuberculoma in 1 and thrombophlebitis in 1. Conclusions: Our series shows that cavernous sinus syndrome occurs at any age and equally in both sexes. Optic neuropathy is common. Inflammatory diseases were found to be the most frequent cause of the syndrome in this series.

          Related collections

          Most cited references17

          • Record: found
          • Abstract: found
          • Article: not found

          Cavernous sinus syndrome. Analysis of 151 cases.

          To characterize lesions causing cavernous sinus syndrome. Review of 26 years of personal experience in a large city hospital. Among 151 patients, tumors (45 patients, 30%) were the most frequent cause of cavernous sinus syndrome. However, when surgical causes (17 patients, 11%) were included, trauma (36 patients, 24%) became most common. Self-limited inflammation was the third frequent cause (34 patients, 23%), while carotid aneurysms and fistulas, infection, and other causes composed the remaining 12%. The age at onset varied with the cause, and patients with aneurysms (average age, 52 years) and patients with tumors (average age, 47 years) were older than those with self-limited inflammation (average age, 35 years) and trauma (average age, 29 years). Spontaneous remissions defined "self-limited inflammation" but were also seen following an acute onset of symptoms due to aneurysms and pituitary apoplexy. In an unselected series from a city hospital, tumor, trauma, and self-limited inflammation were the predominant causes of cavernous sinus syndrome, and classic causes such as aneurysm, meningioma, and bacterial infection were uncommon. Contrast-enhanced magnetic resonance imaging and watchful waiting proved the most effective diagnostic procedures.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Cranial pachymeningitis of unknown origin: a study of seven cases.

            We report seven patients with cranial pachymeningitis of unknown origin in whom the main clinical features were headaches, ataxia, and cranial nerve palsies. CSF showed inflammatory changes. CT and MRI showed thickening of the falx and of the tentorium. The clinical course was chronic. Four patients improved with prednisolone but became steroid-dependent: in two cases, radiotherapy had no lasting improvement and in one, azathioprine permitted a reduction of the corticosteroids. Five patients had biopsy of the tentorium cerebelli or of the temporal dura mater. In two cases, autopsy revealed extensive pachymeningitis without parenchymal changes. In all instances, microscopic examination of the dura mater showed a cellular infiltrate of polymorphic cells; there were no epithelioid granulomas. Review of the literature discloses seven similar cases. We discuss the relationship of these lesions with inflammatory meningeal masses, the focal pachymeningitis of the Tolosa-Hunt syndrome, and multifocal fibrosis.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              The Tolosa-Hunt syndrome

                Bookmark

                Author and article information

                Contributors
                Role: ND
                Role: ND
                Journal
                abo
                Arquivos Brasileiros de Oftalmologia
                Arq. Bras. Oftalmol.
                Conselho Brasileiro de Oftalmologia (São Paulo, SP, Brazil )
                0004-2749
                1678-2925
                December 1998
                : 61
                : 6
                : 635-639
                Affiliations
                [1] Belo Horizonte Minas Gerais orgnameUniversidade Federal de Minas Gerais orgdiv1Faculdade de Medicina orgdiv2Hospital São Geraldo Brazil
                [2] Belo Horizonte Minas Gerais orgnameUniversidade Federal de Minas Gerais orgdiv1Faculdade de Medicina orgdiv2Hospital São Geraldo Brazil
                Article
                S0004-27491998000600635
                10.5935/0004-2749.19980005
                0d503b14-ce4f-4afb-8a66-c997b49f1e55

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 18, Pages: 5
                Product

                SciELO Brazil


                Síndrome do seio cavernoso,Cefaléia,Oftalmoplegia,Neuropatia óptica,Cavernous sinus syndrome,Headache,Ophthalmoplegia,Optic neuropathy

                Comments

                Comment on this article