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Inorganic-Organic Hybrid Nanomaterials for Therapeutic and Diagnostic Imaging Applications

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      Nanotechnology offers outstanding potential for future biomedical applications. In particular, due to their unique characteristics, hybrid nanomaterials have recently been investigated as promising platforms for imaging and therapeutic applications. This class of nanoparticles can not only retain valuable features of both inorganic and organic moieties, but also provides the ability to systematically modify the properties of the hybrid material through the combination of functional elements. Moreover, the conjugation of targeting moieties on the surface of these nanomaterials gives them specific targeted imaging and therapeutic properties. In this review, we summarize the recent reports in the synthesis of hybrid nanomaterials and their applications in biomedical areas. Their applications as imaging and therapeutic agents in vivo will be highlighted.

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            Author and article information

            [1 ] Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
            [2 ] Department of Bioenvironmental Engineering, Chung Yuan Christian University, Chung Li, 32023, Taiwan; E-Mail: yt_huang@
            Author notes
            [* ]Author to whom correspondence should be addressed; E-Mail: jlvivero@ ; Tel.: +1-919-448-1752.

            These authors contributed equally to this work.

            Int J Mol Sci
            International Journal of Molecular Sciences
            Molecular Diversity Preservation International (MDPI)
            10 June 2011
            : 12
            : 6
            : 3888-3927
            © 2011 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

            This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (



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