Li Luo: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: MethodologyRole:
SoftwareRole: VisualizationRole: Writing – original draftRole: Writing – review &
editing
Huining Kang:
ORCID: http://orcid.org/0000-0002-4415-3573
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: SoftwareRole: VisualizationRole: Writing – original draftRole: Writing
– review & editing
Xichen Li: Role: Data curationRole: Formal analysisRole: Writing – review & editing
Scott A. Ness: Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: Writing –
review & editing
Christine A. Stidley: Role: ConceptualizationRole: MethodologyRole: VisualizationRole: Writing – review
& editing
Zhaohui Qin: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
9
October
2020
Publication date Collection: 2020
Volume: 15
Issue: 10
Electronic Location Identifier: e0232646
Affiliations
[1
]
Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico
[2
]
University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico
[3
]
Department of Mathematics and Statistics, University of New Mexico, Albuquerque, New
Mexico
Emory University Rollins School of Public Health, UNITED STATES
Author notes
Competing Interests: NO authors have competing interests
Author information
Article
Publisher ID:
PONE-D-20-11155
DOI: 10.1371/journal.pone.0232646
PMC ID: 7546511
PubMed ID: 33035235
SO-VID: 0d83ef8e-e10e-4699-b0e2-9c58d5fc68c2
Copyright © © 2020 Luo et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000054, National Cancer Institute;
Award ID: R01CA170250
Award Recipient
:
Scott A. Ness
Funded by: funder-id http://dx.doi.org/10.13039/100000072, National Institute of Dental and Craniofacial Research;
Award ID: R01DE023222
Award Recipient
:
Scott A. Ness
Funded by: funder-id http://dx.doi.org/10.13039/100000054, National Cancer Institute;
Award ID: P30CA118100
This work was supported by grants from the National Institutes of Health (
https://www.nih.gov/) National Cancer Institute (R01CA170250 to S.A.N.), National Institute of Dental
and Craniofacial Research (R01DE023222 to S.A.N.), and was partially supported by
UNM Comprehensive Cancer Center Support Grant NCI P30CA118100, the Biostatistics Shared
Resource, and Analytical and Translational Genomics Shared Resource. The computational
resources used in this work were provided by the University of New Mexico Center for
Advanced Research Computing. The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Identification and Analysis
Subject:
Genetic Screens
Subject:
Physical Sciences
Subject:
Mathematics
Subject:
Probability Theory
Subject:
Random Variables
Subject:
Covariance
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
RNA processing
Subject:
RNA splicing
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
RNA processing
Subject:
RNA splicing
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Macromolecular structure analysis
Subject:
RNA structure
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
RNA structure
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
Molecular biology assays and analysis techniques
Subject:
Nucleic acid analysis
Subject:
RNA analysis
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
Molecular biology assays and analysis techniques
Subject:
Nucleic acid analysis
Subject:
RNA analysis
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
RNA processing
Subject:
Alternative Splicing
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
RNA processing
Subject:
Alternative Splicing
Subject:
Research and Analysis Methods
Subject:
Simulation and Modeling
