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      The arrival of SARS-CoV-2 in Venezuela

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          Abstract

          We read with interest the World Report about the impact of coronavirus disease 2019 (COVID-19) on Venezuelan migrants. 1 We concur wholeheartedly that the COVID-19 pandemic will have a negative impact on Venezuelans who have taken refuge in neighbouring countries. A daunting situation is unfolding within Venezuela, which deserves immediate international attention. Almost 2 years ago, after the collapse of health-care services and multiple concurrent re-emerging diseases outbreaks, the US Centers for Disease Control and Prevention issued the ongoing recommendation that travellers should avoid all non-essential travel to Venezuela. 2 The arrival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is therefore a major challenge for the country's already fragile systems. The economic collapse in Venezuela and lack of investment in health care has dramatically decreased the number of hospital beds to care for its population of almost 30 million people. The inventory of hospital beds (23 762 beds) released by the Venezuelan Government 3 on March 23, 2020, overestimates availability because most public health-care centres are currently functioning under technical shutdown due to insufficient essential equipment, consumables, drug inventories, and qualified health-care professionals. Estimates from the National Survey of Venezuelan Hospitals 4 and the non-governmental Venezuelan Defence for Epidemiology Network 1 place the number of critical care beds at approximately 720 nationwide. Hospitals in some high-income countries have not had enough ventilators to support their critically ill patients. In Venezuela, we know of health-care workers nationwide who are concerned about disproportionate difficulties in providing ventilator assistance for patients with COVID-19. By Feb 26, 2020, there were only 102 ventilators across all 23 states and the capital district; half of these were located in hospitals in the capital Caracas, and the other half were unevenly distributed across the rest of the country. 5 It is clear that the demand for beds and ventilators in hospitals across Venezuela will quickly exceed capacity for patients with COVID-19. Tragically, the decline of the industrial and construction sectors and the depletion of resources will affect Venezuela's ability to undertake temporary construction or increase hospital capacities. The poor power infrastructure, which has caused sustained blackouts across the country, and a widespread shortage of fuel will further complicate Venezuela's ability to face the COVID-19 pandemic. Additionally, the absence of running water for 20% of the country 6 and irregular supply for 70% will severely affect the necessary hygiene measures required for SARS-CoV-2 containment. The impact of the ongoing humanitarian crisis on Venezuela's health-care workforce amplifies the country's incapacity to cope with COVID-19. The Venezuelan Medical Federation (Federación Médica Venezolana) has stated that at least 30 000 medical professionals have left the country over the last decade, contributing to a shortage of specialists. 7 Furthermore, the Venezuelan Government continues to threaten physicians and health-care workers with retaliation if they speak out publicly about COVID-19 cases. 8 The first COVID-19 case in Venezuela was reported on March 13, 2020. As of April 28, 2020, there have been 329 confirmed cases reported through government sources; 5 however, this number could be underestimated because of under-testing and under-reporting. The situation will worsen if the Venezuelan Government continues to suppress pertinent epidemiological data, ban disease control initiatives, and hinder international humanitarian support. 9 As health-care capacity is stretched thin, the country will continue to face an epidemiological crisis in which most Venezuelans will endure an undefeatable setting of concurrent epidemics.

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          Venezuelan migrants “struggling to survive” amid COVID-19

          Humanitarian organisations are concerned that border closures and health-care shortages are amplifying the challenges posed by COVID-19. Joe Parkin Daniels reports from Bogotá. The coronavirus disease 2019 (COVID-19) pandemic is exacerbating an already precarious health crisis for Venezuelan migrants fleeing a collapsed health system at home. At the time of going to press, the outbreak is continuing to spread in Venezuela despite a military-enforced quarantine. Venezuela remains mired in economic and social turmoil. Hyperinflation last year reached 10 000%, according to the central bank, while shortages in basic foodstuffs and medical supplies were already a daily reality. Hospitals regularly facing power outages and basic medical supplies—from latex gloves to routine antibiotics—are often hard to come by. 4·5 million people have fled Venezuela in recent years, including health workers and disease specialists. Most Venezuelan migrants cross on foot into neighbouring Colombia, which houses an estimated 1·4 million Venezuelans. In Cúcuta, a city on the Colombian side of the border, as many as 40 000 Venezuelans arrived daily until March 14, when Colombia closed its borders in a bid to stem the spread of COVID-19. Colombia had 306 confirmed cases of the disease, with three deaths, as of March 24. The seven official entry points along the 1378-mile border remain closed, although countless informal crossings are still in use. The International Rescue Committee, a non-governmental organisation (NGO) with a clinic for Venezuelan migrants in Cúcuta, reports an emerging crisis. “Needs are very strongly felt here in terms of access to health and other services”, said Minerva Márquez, the NGO's representative in Cúcuta. “Migrants are struggling to survive without soup kitchens or any means of work. Few partner organisations are able to work at full capacity either.” The Colombian government has returned a number of migrants to Venezuela in response to the outbreak, while permitting those with ongoing medical treatments—including dialysis—to cross into Colombia. It is unclear how many people have been returned or how many have able to cross the border as medical exceptions; humanitarian actors report that the Colombian authorities are working on a case-by-case basis. The Pan American Health Organization announced on March 16 that it will facilitate cooperation between the two countries in battling the spread of COVID-19 on the border, despite the breakdown in diplomatic relations a year ago. Other NGOs have expressed concerns about what effects the border shutdown could have. Ellen Rymshaw, Colombia's head of mission at Médecins Sans Frontières (MSF), said that fewer patients have attended their clinics in border provinces since the shutdown. “We are also seeing an increase of xenophobia and discrimination against this population, which is falsely accused of the spread of COVID-19 in the border areas. MSF is extremely concerned that the growing xenophobia toward the Venezuelan community will prevent access to basic medical services they so desperately need.” Both countries have also announced strict quarantines, preventing many of those wishing to return home from doing so. Even if they could, the Venezuelan health system continues to buckle. A survey of doctors by the local Venezuelan NGO Médicos Unidos found that only 25% of respondents had reliable tap water in their hospitals and clinics. 65% said they did not have gloves, masks, soap, goggles, or scrubs. At one of the country's largest hospitals, the University Hospital of Caracas, 80% of health workers reported being without protective equipment. José Félix Oletta, Venezuela's health minister from 1997 to 1999, said that while the health system is “unprepared” for the COVID-19 pandemic, professionals will still do everything they can. “We are used to witnessing complex scenarios, of uncertainty, and rationalising our behaviours, and this gives us a shield against fear”, he told The Lancet. Venezuela's health crisis is also a political one. Nicolás Maduro sits in Miraflores, the presidential palace, although a US-led coalition of more than 50 countries does not recognise him as the legitimate leader. Instead, those countries back Juan Guaidó, a young opposition leader who declared himself Venezuela's legitimate president in January, last year. The deadlock was never resolved, and opposition supporters and international observers say that the Maduro administration's intransigence has contributed to the crisis. Maduro says that sweeping US-led sanctions are hamstringing Venezuela's ability to respond to the pandemic, prohibiting the country from importing medicines and supplies. He requested US$5 billion from the International Monetary Fund to tackle the outbreak, which was rebuffed on March 18. He subsequently asked for $1 billion, Bloomberg News reported.
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            Author and article information

            Contributors
            Journal
            Lancet
            Lancet
            Lancet (London, England)
            Elsevier Ltd.
            0140-6736
            1474-547X
            4 May 2020
            4 May 2020
            Affiliations
            [a ]Academia Nacional de Medicina, Caracas 1012, Venezuela
            [b ]Icahn School of Medicine at Mount Sinai, New York, NY, USA
            [c ]Infectious Diseases Research Incubator and the Zoonosis and Emerging Pathogens Regional Collaborative Network, Barquisimeto, Venezuela
            [d ]Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnologica de Pereira, Pereira, Risaralda, Colombia
            Article
            S0140-6736(20)31053-9
            10.1016/S0140-6736(20)31053-9
            7198211
            32380043
            0d8706cf-414e-414d-a03b-d9b582f78864
            © 2020 Elsevier Ltd. All rights reserved.

            Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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