Neural and molecular correlates of psychological pain during major depression, and its link with suicidal ideas.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Psychological pain increases the risk of suicidal ideas and acts, and represents a potential therapeutic target. However, the mechanisms of mental pain remain unclear. Here, we assessed the peripheral transcriptomic and central neural correlates of mental pain during a depressive episode.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Prog. Neuropsychopharmacol. Biol. Psychiatry

Title: Progress in neuro-psychopharmacology & biological psychiatry

Publisher: Elsevier BV

ISSN (Electronic): 1878-4216

ISSN (Print): 0278-5846

Publication date (Electronic): June 08 2020

Volume: 100

Affiliations

[1 ] McGill University, Department of Psychiatry & Douglas Mental Health University Institute, McGill Group for Suicide Studies, Montréal, Québec, Canada; Université de Paris (ex-Université Paris-Descartes), Paris, France; Clinique des Maladies Mentales et de l'Encéphale (CMME), CH Sainte-Anne, GHU Paris Psychiatrie et Neurosciences, Paris, France; Nîmes Academic Hospital (CHU), Nîmes, France. Electronic address: fabrice.jollant@parisdescartes.fr.

[2 ] Nîmes Academic Hospital (CHU), Nîmes, France.

[3 ] McGill University, Department of Psychiatry & Douglas Mental Health University Institute, McGill Group for Suicide Studies, Montréal, Québec, Canada.

[4 ] McGill University, Department of Psychiatry & Douglas Mental Health University Institute, McGill Group for Suicide Studies, Montréal, Québec, Canada; Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, Strasbourg, France; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France.

[5 ] McGill University, Department of Psychiatry & Douglas Mental Health University Institute, McGill Group for Suicide Studies, Montréal, Québec, Canada; Institut de Neurosciences de la Timone, UMR7289, CNRS Aix-Marseille Université, Marseille, France; AP-HM, Pôle de Psychiatrie, Marseille, France.

Article

Publisher Item ID: S0278-5846(19)30781-X

DOI: 10.1016/j.pnpbp.2020.109909

PubMed ID: 32145361

SO-VID: 0da95ed5-5ffa-4fe0-ada3-d8a3b11600ad

History

Keywords: Psychological pain,Transcriptomics,Nociceptin,Serotonin,Neuroimaging

Data availability:

Keywords: Psychological pain, Transcriptomics, Nociceptin, Serotonin, Neuroimaging

Neural and molecular correlates of psychological pain during major depression, and its link with suicidal ideas.

Read this article at

Abstract

Related collections

NeuroImaging Methods

Author and article information

Journal

Affiliations

Article

History

Comments

Comment on this article

Similar content 20

Cited by 7