Blog
About

5
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Possible treatment of pre-eclampsia with calcium channel blocking agents.

      Medical Hypotheses

      drug effects, Vasoconstriction, drug therapy, Pregnancy Complications, Cardiovascular, Pregnancy, physiopathology, etiology, Pre-Eclampsia, blood supply, Placenta, therapeutic use, Nifedipine, Hypertension, Humans, Fetus, Female, Eclampsia, Calcium Channel Blockers

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          A review of the pathophysiology and treatment of pre-eclampsia indicates that vasospasm and vascular hyperreactivity are important elements in the disease process and its control. Five requirements for a therapeutic agent in pre-eclampsia are identified: control of generalized vasospasm, hypertension, and eclamptic convulsions, maintenance of placental perfusion, and lack of adverse effects on the fetus/neonate. Calcium channel blocking agents are well known arteriolar vasodilators and inhibitors of coronary artery vasospasm, and appear to possess qualities relevant to these therapeutic requirements for pre-eclampsia. It is proposed that calcium channel blocking agents may be effective agents in the management of pre-eclampsia.

          Related collections

          Author and article information

          Journal
          6366485

          Comments

          Comment on this article