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      Vitamin D supplementation review and recommendations for women diagnosed with breast or ovary cancer in the context of bone health and cancer prognosis/risk.

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          Abstract

          Vitamin D review and supplementation recommendations for women diagnosed with breast or ovary cancer have been defined in the context of bone health and cancer prognosis/risk taking as reference wider cancer patients and postmenopausal women. This specific group has been selected due to its higher osteoporosis risk versus postmenopausal women. Early vitamin D supplementation could help maintain bone health, as well as potentially enhance cancer survival rate. Factors considered for supplementation include daily dose, periodicity, chemical form, administration, and serum levels. Sufficient vitamin D serum levels are recommended to be above 30 ng/ml (75 nmol/l). Maintenance oral supplementation equivalent to a minimum daily dosage of 800-1000 IU (20-25 μg) cholecalciferol provided in a daily to monthly bases is preferred, also advised to start with higher dosages when vitamin D serum levels are <10 ng/ml (25 nmol/l). Calcidiol supplementation is more effective, making it advantageous for cases with very low or difficult to raise vitamin D serum levels.

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          Author and article information

          Journal
          Crit. Rev. Oncol. Hematol.
          Critical reviews in oncology/hematology
          1879-0461
          1040-8428
          Oct 2015
          : 96
          : 1
          Affiliations
          [1 ] Department of Medical Oncology, Hospital La Zarzuela, Madrid, Spain. Electronic address: amartinherranz@hotmail.com.
          [2 ] Department of Medical Oncology, Hospital La Zarzuela, Madrid, Spain.
          Article
          S1040-8428(15)00095-5
          10.1016/j.critrevonc.2015.05.006
          26068240
          0ddb3ecd-d369-45e7-a63c-62e7d767b822
          Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
          History

          Bone,Cancer,Osteoporosis,Post-menopause,Prognosis,Supplementation,Vitamin D

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