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      ESPE and PES International Survey of Centers and Clinicians Delivering Specialist Care for Children and Adolescents with Gender Dysphoria

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          Abstract

          Background/Aims: Increasing numbers of children and adolescents seek medical care because they experience incongruence between their physical sex and their gender identity. Methods: The ESPE working group on gender dysphoria (GD) undertook a survey to investigate the structure and the type of medical care in centers that offer specialist care for transgender adolescents. Results: The personnel of each center varied from country to country, and a nationally organized network or plan for managing GD did not exist in all centers. The majority of young people were transitioning from female to male, and the number of new referrals increased remarkably during the past 3 years. Almost all centers follow the guidelines issued by the Endocrine Society and World Professional Association for Transgender Health. GnRH analogues were used as the initial treatment in the majority of the centers. The age from which adolescents are treated with gender-affirming hormones varied between centers. Several legal restrictions that concern or influence the treatment of children and adolescents with GD were finally addressed. Conclusion: This first international survey examining the variations in availability and provisions of services for children and adolescents with GD serves as a starting block for further dialogue and future studies.

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          Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society* Clinical Practice Guideline

          To update the "Endocrine Treatment of Transsexual Persons: An Endocrine Society Clinical Practice Guideline," published by the Endocrine Society in 2009.
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            Evidence for an altered sex ratio in clinic-referred adolescents with gender dysphoria.

            The number of adolescents referred to specialized gender identity clinics for gender dysphoria appears to be increasing and there also appears to be a corresponding shift in the sex ratio, from one favoring natal males to one favoring natal females.
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              Children and adolescents with gender identity disorder referred to a pediatric medical center.

              To describe the patients with gender identity disorder referred to a pediatric medical center. We identify changes in patients after creation of the multidisciplinary Gender Management Service by expanding the Disorders of Sex Development clinic to include transgender patients.
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                Author and article information

                Journal
                HRP
                Horm Res Paediatr
                10.1159/issn.1663-2818
                Hormone Research in Paediatrics
                S. Karger AG
                1663-2818
                1663-2826
                2018
                March 2019
                29 January 2019
                : 90
                : 5
                : 326-331
                Affiliations
                [_a] aDivision of Pediatric Endocrinology, Paedi Center for Specialized Pediatrics, Nicosia, Cyprus
                [_b] bUniversity of Nicosia Medical School, Nicosia, Cyprus
                [_c] cDepartment of Paediatric and Adolescent Endocrinology, University College London Hospitals, London, United Kingdom
                [_d] dUCL Great Ormond Street Institute of Child Health, London, United Kingdom
                [_e] eUK Gender Identity Development Service, Tavistock and Portman NHS Trust, London, United Kingdom
                [_f] fDepartment of Medical Ethics and Health Law, Leiden University Medical Centre, Leiden, The Netherlands
                [_g] gDepartment of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands
                [_h] hDepartment of Growth and Reproduction and EDMaRC, Rigshospitalet, Faculty of Health Sciences, Copenhagen University, Copenhagen, Denmark
                Author notes
                *Nicos Skordis, MD, PhD, Paedi Center for Specialized Pediatrics, Athalassas Avenue 178, CY–2025 Nicosia (Cyprus), E-Mail nicosskordis@paedi.org.cy
                Article
                496115 Horm Res Paediatr 2018;90:326–331
                10.1159/000496115
                30695784
                0e11134d-3275-46d6-bbf9-a9520ecc7228
                © 2019 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                : 03 July 2018
                : 10 December 2018
                Page count
                Figures: 1, Tables: 5, Pages: 6
                Categories
                Original Paper

                Endocrinology & Diabetes,Neurology,Nutrition & Dietetics,Sexual medicine,Internal medicine,Pharmacology & Pharmaceutical medicine
                Gender-affirming hormones,Adolescents,Gender dysphoria

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