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      Comparison of Creatinine Secretion in Men and Women

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      Nephron

      S. Karger AG

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          Abstract

          The exogenous creatinine: inulin clearance ratio was measured in a series of human subjects to determine whether or not a sex difference existed in the renal tubular handling of creatinine. The average clearance ratio was 1.25 and was not affected by the sex of the subject, nor in women, by the phase of the menstrual cycle, nor the complete absence of the adrenal glands. It is concluded that a species difference exists in the renal tubular handling of creatinine, as these findings contrast sharply with the results seen in rats and dogs.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1966
          1966
          26 November 2008
          : 3
          : 4
          : 201-205
          Affiliations
          University of Michigan, Ann Arbor, Mich.
          Article
          179534 Nephron 1966;3:201–205
          10.1159/000179534
          5958981
          © 1966 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 5
          Categories
          Paper

          Cardiovascular Medicine, Nephrology

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