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      Surgical clipping or endovascular coiling for unruptured intracranial aneurysms: a pragmatic randomised trial.

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          Abstract

          Unruptured intracranial aneurysms (UIAs) are increasingly diagnosed and are commonly treated using endovascular treatment or microsurgical clipping. The safety and efficacy of treatments have not been compared in a randomised trial. How to treat patients with UIAs suitable for both options remains unknown.

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          Author and article information

          Journal
          J. Neurol. Neurosurg. Psychiatry
          Journal of neurology, neurosurgery, and psychiatry
          BMJ
          1468-330X
          0022-3050
          Aug 2017
          : 88
          : 8
          Affiliations
          [1 ] Department of Surgery, Division of Neurosurgery, University of Alberta, Edmonton, Canada.
          [2 ] Service de Neurochirurgie, CHU Cavale Blanche, INSERM UMR 1101 LaTIM, Brest, France.
          [3 ] Department of Radiology, Service of Neuroradiology, Centre Hospitalier de l'Université de Montréal (CHUM), Notre-Dame Hospital, Montreal, Canada.
          [4 ] Department of Surgery, Service of Neurosurgery, Centre Hospitalier de l'Université de Montréal (CHUM), Notre-Dame Hospital, Montreal, Canada.
          [5 ] Department of Medical Imaging, Section of Neuroradiology, University of Ottawa, The Ottawa Hospital, Ottawa, Canada.
          [6 ] Department of Surgery, Section of Neurosurgery, University of Ottawa, The Ottawa Hospital, Ottawa, Canada.
          [7 ] Department of Neurosurgery, Centre Hospitalier Universitaire de Liège, Liège, Belgium.
          [8 ] Division of Neurosurgery, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.
          [9 ] Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Canada.
          [10 ] Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
          [11 ] Department of Neurosurgery, Semmes-Murphey Neurologic and Spine Institute, University of Tennessee, Memphis, USA.
          [12 ] Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, California, USA.
          [13 ] Department of Mathematics and Statistics, Université de Montréal, Montreal, Canada.
          [14 ] Research Centre, Centre Hospitalier de l'Université de Montréal (CHUM), Notre-Dame Hospital, Montreal, Canada.
          Article
          jnnp-2016-315433
          10.1136/jnnp-2016-315433
          28634280
          0e214353-ddde-4fea-b393-6c65ed355839
          History

          randomized controlled trial,pragmatic trial,endovascular coiling,surgical clipping,unruptured intracranial aneurysm

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