Jothilingam Sivapackiam:
ORCID: http://orcid.org/0000-0001-7979-1893
Role: Data curationRole: Formal analysisRole: InvestigationRole: Validation
Shivesh Kabra: Role: Data curationRole: Formal analysisRole: Investigation
Sylvia Speidel: Role: Data curationRole: Formal analysisRole: Investigation
Monica Sharma: Role: InvestigationRole: Writing – review & editing
Richard Laforest: Role: Formal analysisRole: InvestigationRole: Validation
Amber Salter: Role: Formal analysis
Michael P. Rettig: Role: Data curationRole: Formal analysisRole: InvestigationRole: Methodology
Vijay Sharma:
ORCID: http://orcid.org/0000-0002-4985-0044
Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
ResourcesRole: SupervisionRole: Writing – original draftRole: Writing – review & editing
Juri G. Gelovani: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
23
May
2019
Publication date Collection: 2019
Volume: 14
Issue: 5
Electronic Location Identifier: e0215579
Affiliations
[1
]
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St.
Louis, MO, United States of America
[2
]
Pediatrics Cardiology, Washington University School of Medicine, St. Louis, MO, United
States of America
[3
]
Department of Biostatistics, Washington University School of Medicine, St. Louis,
MO, United States of America
[4
]
Division of Oncology, Department of Medicine, Washington University School of Medicine,
St. Louis, MO, United States of America
[5
]
Department of Neurology, Washington University School of Medicine, St. Louis, MO,
United States of America
[6
]
Department of Biomedical Engineering, School of Engineering & Applied Science, Washington
University, St. Louis, MO, United States of America
Wayne State University, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-18-25533
DOI: 10.1371/journal.pone.0215579
PMC ID: 6532866
PubMed ID: 31120912
SO-VID: 0e5fa93e-12cb-4a96-931d-48c34c5812cc
Copyright © © 2019 Sivapackiam et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: HL111163
Award Recipient
:
ORCID: http://orcid.org/0000-0002-4985-0044
Vijay Sharma
Funded by: funder-id http://dx.doi.org/10.13039/100000009, Foundation for the National Institutes of Health;
Award ID: RO1 HL142297
Award Recipient
:
ORCID: http://orcid.org/0000-0002-4985-0044
Vijay Sharma
This study was supported in parts by grants RO1 HL111163 (VS) and RO1 HL142297 (VS)
from the National Institutes of Health. The funding agencies had no role in study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Bioenergetics
Subject:
Energy-Producing Organelles
Subject:
Mitochondria
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Structures and Organelles
Subject:
Energy-Producing Organelles
Subject:
Mitochondria
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
In Vivo Imaging
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Heart
Subject:
Myocardium
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Heart
Subject:
Myocardium
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Alcohols
Subject:
Ethanol
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Alcohols
Subject:
Ethanol
Subject:
Medicine and Health Sciences
Subject:
Cardiology
Subject:
Cardiomyopathies
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Electrophysiology
Subject:
Membrane Potential
Subject:
Depolarization
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Electrophysiology
Subject:
Membrane Potential
Subject:
Depolarization
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cell Processes
Subject:
Cell Death
Subject:
Apoptosis
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Neuroimaging
Subject:
Positron Emission Tomography
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Neuroimaging
Subject:
Positron Emission Tomography
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Medicine and Health Sciences
Subject:
Radiology and Imaging
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography