6
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Primary prevention for rheumatic Fever: progress, obstacles, and opportunities.

      1 , 2

      Global heart

      Elsevier BV

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Acute rheumatic fever and rheumatic heart disease are noninfectious sequelae of group A streptococcal pharyngeal infection. These diseases represent a huge public health burden in developing countries with significant mortality and morbidity. Early diagnosis and appropriate antibiotic treatment with group A streptococcal pharyngitis provides an opportunity for prevention of acute rheumatic fever and rheumatic heart disease. The use of locally adapted clinical algorithms for diagnosing group A streptococcal pharyngitis has great potential in resource-poor settings for earlier diagnosis and early treatment. Intramuscular penicillin is the drug of choice in developing country settings. Recent work has demonstrated the cost-effectiveness of a treat-all strategy with intramuscular penicillin, whereas incorporating a clinical decision rule remains the preferred strategy. We strongly support the adoption of a comprehensive prevention and control program for acute rheumatic fever and rheumatic heart disease, incorporating primary prevention, as critical to underpinning the efforts in many parts of the world to stem the tide of this devastating disease.

          Related collections

          Author and article information

          Journal
          Glob Heart
          Global heart
          Elsevier BV
          2211-8179
          Sep 2013
          : 8
          : 3
          Affiliations
          [1 ] University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa. Electronic address: liesl.zuhlke@uct.ac.za.
          [2 ] Department of Cardiology, All India Institute of Medical sciences, New Delhi, India.
          Article
          S2211-8160(13)00111-7
          10.1016/j.gheart.2013.08.005
          25690499

          Comments

          Comment on this article