There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Disturbances in the expression/function of the 5-HT2A receptor are implicated in autism.
The association of the 5-HT2A receptor gene with autism was studied in the Croatian
population. Distribution frequencies for alleles, genotypes and haplotypes of -1438
A/G and His452Tyr polymorphisms were compared in samples of 103 autistic and 214 control
subjects. Significant overrepresentation of the G allele and the GG genotype of the
-1438 A/G polymorphism was observed in group of autistic subjects, supporting the
possible involvement of the 5-HT2A receptor in the development of autism.
Copyright (c) 2010 Elsevier Ltd. All rights reserved.