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      Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma.

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          Abstract

          Patients with malignant pleural mesothelioma, a rapidly progressing malignancy with a median survival time of 6 to 9 months, have previously responded poorly to chemotherapy. We conducted a phase III trial to determine whether treatment with pemetrexed and cisplatin results in survival time superior to that achieved with cisplatin alone.

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          Author and article information

          Journal
          J Clin Oncol
          Journal of clinical oncology : official journal of the American Society of Clinical Oncology
          American Society of Clinical Oncology (ASCO)
          0732-183X
          0732-183X
          Jul 15 2003
          : 21
          : 14
          Affiliations
          [1 ] University of Chicago, Cancer Research Center, 5841 South Maryland Ave, Chicago, IL 60637, USA. nvogelza@medicine.bsd.uchicago.edu.
          Article
          JCO.2003.11.136
          10.1200/JCO.2003.11.136
          12860938
          a3280ea9-14c6-495e-9232-828419cb2c91

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