Predictors of Cardiovascular Death in Patients with a Left Ventricular Restrictive Filling Pattern of the Mitral Inflow

Abstract

The survival, clinical and echocardiographic variables and the predictors of cardiovascular death were determined for a group of 168 patients (mean age 63 ± 13 years; 65 females; mean left ventricular ejection fraction 32 ± 10%) with restrictive filling of the left ventricle and depressed systolic function after a mean follow-up period of 2.7 ± 1 years. Shorter deceleration time (DT) of the mitral inflow was the only variable significantly different between survivors and nonsurvivors (p < 0.05) and the only predictor of death found by multivariate logistic regression analysis (odds ratio 2.2, 95% confidence interval 1.7–3.6). In this patient population, a DT of the early wave of the mitral inflow <140 ms identified the patients with the highest risk of cardiac death. DT is a practical echocardiographic parameter for risk stratification of patients with significant left ventricular systolic dysfunction and restrictive filling of the left ventricle.

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 2005

Publication date (Print): November 2004

Publication date (Electronic): 24 November 2004

Volume: 103

Issue: 1

Pages: 48-52

Affiliations

^aOdessa Heart Institute, Odessa, Tex., ^bDivision of Cardiology, University of Texas Medical School Houston, Houston, Tex., ^cSt. Francis Hospital, Stony Brook University, SUNY, Roslyn, N.Y., USA

Article

Publisher ID: 81852 Other ID: Cardiology 2005;103:48–52

DOI: 10.1159/000081852

PubMed ID: 15528901

Copyright statement: © 2005 S. Karger AG, Basel

License:

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Page count

Figures: 1, Tables: 2, References: 26, Pages: 5

Product

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Categories

Subject: Noninvasive and Diagnostic Cardiology