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      • Record: found
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      • Article: found

      Formation of Radiation Cataracts in Rats after Monolateral Carotid Ligature

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          Abstract

          X-ray cataracts in rats were shown in an earlier paper to be enhanced by a unilateral common carotid ligature. It was the aim of the present paper to investigate lens wet weights, protein concentrations and several specific enzyme activities in the lenses of these animals. Irradiated lenses weighed less than controls. Carotid ligatures further reduced wet weight only after previous X-irradiation. Protein concentrations were slightly reduced in irradiated lenses and it appeared that opacification was accompanied by diminished protein synthesis and growth rate. Few changes of specific enzyme activities were noted and they are probably indirect consequences of the radiation injury.

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1977
          Publication date (Print): 1977
          Publication date (Electronic): 03 December 2009
          Volume: 9
          Issue: 1
          Pages: 31-37
          Affiliations
          Clinical Institute of Experimental Ophthalmology, Department of Biochemistry of the Eye, University of Bonn, Bonn
          Article
          Publisher ID: 264864 Other ID: Ophthalmic Res 1977;9:31–37
          DOI: 10.1159/000264864
          SO-VID: 0f1d860d-0078-453a-91f6-0dbff8b9dccc
          Copyright © © 1977 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 09 February 1976
          Date accepted : 04 February 1977
          Page count
          Pages: 7
          Categories
          Subject: Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Rat,Carotid ligature,Soluble lens proteins,Specific enzyme activities,X-rays,Cataract,Lens wet weight
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Rat, Carotid ligature, Soluble lens proteins, Specific enzyme activities, X-rays, Cataract, Lens wet weight

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