A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus

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Abstract

<p class="first" id="d3722896e223">The indirect water-deprivation test is the current reference standard for the diagnosis of diabetes insipidus. However, it is technically cumbersome to administer, and the results are often inaccurate. The current study compared the indirect water-deprivation test with direct detection of plasma copeptin, a precursor-derived surrogate of arginine vasopressin. </p>

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Journal

Title: New England Journal of Medicine

Abbreviated Title: N Engl J Med

Publisher: New England Journal of Medicine (NEJM/MMS)

ISSN (Print): 0028-4793

ISSN (Electronic): 1533-4406

Publication date Created: August 02 2018

Publication date (Print): August 02 2018

Volume: 379

Issue: 5

Pages: 428-439

Affiliations

[1 ]From the University of Leipzig, Department of Endocrinology and Nephrology (W.F., A.T.), and Leipzig University Medical Center, Integrated Research and Treatment Center Adiposity Diseases (W.F.), Leipzig, the Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg (I.C., M.K., M.F.), and the Clinical Trial Center (U.M.) and Central Laboratory (M.F.), University Hospital Würzburg, Würzburg, Medizinische Klinik und Poliklinik IV, Ludwig...

Article

DOI: 10.1056/NEJMoa1803760

PubMed ID: 30067922

SO-VID: 0fa552b4-d468-4f7e-bf71-a7833f4ab4fd

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http://www.nejmgroup.org/legal/terms-of-use.htm

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