Bioactivity-integrated UPLC/Q-TOF-MS of Danhong injection to identify NF-κB inhibitors and anti-inflammatory targets based on endothelial cell culture and network pharmacology.

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Abstract

Danhong injection (DHI) is a traditional Chinese medicine injection that has been widely used in therapy for cardiovascular diseases. However, neither its mechanism nor its active constituents are clearly understood.

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Journal ID (iso-abbrev): J Ethnopharmacol

Title: Journal of ethnopharmacology

Publisher: Elsevier BV

ISSN (Electronic): 1872-7573

ISSN (Print): 0378-8741

Publication date (Electronic): Nov 04 2015

Volume: 174

Affiliations

[1 ] State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.

[2 ] State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. Electronic address: wxy@tjutcm.edu.cn.

Article

Publisher Item ID: S0378-8741(15)30093-3

DOI: 10.1016/j.jep.2015.08.026

PubMed ID: 26319960

SO-VID: 0fa6c09f-949f-482a-99cf-d59c335ab327

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Keywords: Anti-inflammatory,Danhong injection,NF-kB,Network pharmacology,UPLC/Q-TOF–MS

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Keywords: Anti-inflammatory, Danhong injection, NF-kB, Network pharmacology, UPLC/Q-TOF–MS

Bioactivity-integrated UPLC/Q-TOF-MS of Danhong injection to identify NF-κB inhibitors and anti-inflammatory targets based on endothelial cell culture and network pharmacology.

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Network and Systems Medicine

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