A novel Bunyavirus from the soft tick, Argas vespertilionis,
in Japan

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Soft ticks, Argas vespertilionis, were collected from feces of bats in Japan. Cytopathic effect (CPE) was observed after inoculating the homogenates of ticks to Vero cells. Sequencing of RNA extracted from the cell supernatant was performed by next generation sequencer. The contigs had identity to segments of Bunyaviruses, Issyk-Kul virus. The identities of segment L, M and S were only 77, 76 and 79% to Issyk-Kul virus, respectively. Therefore, we named this novel virus Soft tick bunyavirus (STBV). In the phylogenetic tree, segment L of STBV was closely related to a cluster consisting of the genus Nairovirus of the family Bunyaviridae.

Related collections

Most cited references 3

Record: found
Abstract: found
Article: not found

Nairobi sheep disease virus, an important tick-borne pathogen of sheep and goats in Africa, is also present in Asia.

Beate I Marczinke, Stuart T. Nichol (2002)

Nairobi sheep disease (NSD) virus is the prototype of the tick-borne NSD serogroup, genus Nairovirus, family Bunyaviridae. It is highly pathogenic for sheep and goats, causes disease in humans, and is widespread throughout East Africa. Ganjam virus has caused disease in goats and humans in India. Due to their occurrence on different continents and association with different ticks, these viruses were considered distinct despite serologic cross-reactivity. Their S RNA genome segments and encoded nucleocapsid proteins were found to be 1590 nucleotides and 482 amino acids in length and differed by only 10 and 3% at nucleotide and amino acid levels, respectively. Genetic and serologic data demonstrate that Ganjam virus is an Asian variant of NSD virus. These viruses were phylogenetically more closely related to Hazara virus than Dugbe virus.

0 comments Cited 39 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Hazara virus infection is lethal for adult type I interferon receptor-knockout mice and may act as a surrogate for infection with the human-pathogenic Crimean-Congo hemorrhagic fever virus.

Geoff Pearson, Natasha Merredew, John Chamberlain … (2012)

Hazara virus (HAZV) is closely related to the Crimean-Congo hemorrhagic fever virus (CCHFV). HAZV has not been reported to cause human disease; work with infectious material can be carried out at containment level (CL)-2. By contrast, CCHFV causes a haemorrhagic fever in humans and requires CL-4 facilities. A disease model of HAZV infection in mice deficient in the type I interferon receptor is reported in this study. Dose-response effects were seen with higher doses, resulting in a shorter time to death and earlier detection of viral loads in organs. The lowest dose of 10 p.f.u. was still lethal in over 50 % of the mice. Histopathological findings were identified in the liver, spleen and lymph nodes, with changes similar to a recent mouse model of CCHFV infection. The findings demonstrate that inoculation of mice with HAZV may act as a useful surrogate model for the testing of antiviral agents against CCHFV.

0 comments Cited 27 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

[The taxonomy of the Issyk-Kul virus (ISKV, Bunyaviridae, Nairovirus), the etiologic agent of the Issyk-Kul fever isolated from bats (Vespertilionidae) and ticks Argas (Carios) vespertilionis (Latreille, 1796)].

S Al'khovskiĭ, D K L'vov, M Iu Shchelkanov … (2024)

The Issyk-Kul virus (etiological agent of the Issyk-Kul fever) was originally isolated from bats (Nyctalus noctula Schreber, 1774 (Chiroptera: Vespertilionidae)) and their parasites ticks (Argas (Carios) vespertilionis Latreille, 1796 (Parasitiformes: Argasidae)) in Kirghizia. Sporadic cases and epidemics of the Issyk-Kul fever are observed in Central Asia since 1979. The ISKV genome was de novo sequenced using the next-generation sequencing technology. According to the molecular-genetic and phylogenetic analysis, the ISKV is a member of a novel group in the genus Nairovirus (Bunyaviridae). Based on the data obtained, molecular-genetic methods can be used for ISKV detection (PCR) for the Issyk-Kul fever monitoring and diagnosis in the endemic areas.

0 comments Cited 4 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Journal

Journal ID (nlm-ta): J Vet Med Sci

Journal ID (iso-abbrev): J. Vet. Med. Sci

Journal ID (publisher-id): JVMS

Title: The Journal of Veterinary Medical Science

Publisher: The Japanese Society of Veterinary Science

ISSN (Print): 0916-7250

ISSN (Electronic): 1347-7439

Publication date (Electronic): 25 October 2015

Publication date (Print): March 2016

Volume: 78

Issue: 3

Pages: 443-445

Affiliations

[1) ]Research and Education Center for Prevention of Global Infectious Diseases of Animals, Tokyo University of Agriculture and Technology, 3–5–8 Saiwai-cho, Fuchu, Tokyo 183–8509, Japan

[2) ]Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine and The United Graduate School of Veterinary Science,Yamaguchi University, 1677–1 Yoshida, Yamaguchi 753–8515, Japan

[3) ]Mahara Institute of Medical Acarology, Anan 779–1510, Tokushima, Japan

[4) ]Department of Bacteriology-I, National Institute of Infectious Diseases, 1–23–1 Toyama, Shinjuku-ku, Tokyo 162–8640, Japan

[5) ]University Education Center, University of the Ryukyu, 1 Senbaru, Nishihara-cho, Nakagami-gun, Okinawa 903–0213, Japan

[6) ]Department of Anesthesiology, Saitama Medical University, 38 Moroyama-machi, Iruma-gun, Saitama 350–0495, Japan

[7) ]Faculty of Medical Sciences, University of Fukui, 23–3 Eiheiji, Fukui 910–1193, Japan

[8) ]Department of Virology-I, National Institute of Infectious Diseases, 1–23–1 Toyama, Shinjuku-ku, Tokyo 162–8640, Japan

Author notes

[* ]Correspondence to: Ando, S., Department of Virology-I, National Institute of Infectious Diseases, 1–23–1 Toyama, Shinjuku-ku, Tokyo 162–8640, Japan. e-mail: shuando@ 123456nih.go.jp

Article

Publisher ID: 15-0536

DOI: 10.1292/jvms.15-0536

PMC ID: 4829514

PubMed ID: 26498534

SO-VID: 0fbad20f-f7e7-4c16-88bb-bb3f8cfbf59d

License:

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.

A novel Bunyavirus from the soft tick, Argas vespertilionis, in Japan

Read this article at

Abstract

Related collections

Ticks and tick-borne pathogens

Most cited references 3

Nairobi sheep disease virus, an important tick-borne pathogen of sheep and goats in Africa, is also present in Asia.

Hazara virus infection is lethal for adult type I interferon receptor-knockout mice and may act as a surrogate for infection with the human-pathogenic Crimean-Congo hemorrhagic fever virus.

[The taxonomy of the Issyk-Kul virus (ISKV, Bunyaviridae, Nairovirus), the etiologic agent of the Issyk-Kul fever isolated from bats (Vespertilionidae) and ticks Argas (Carios) vespertilionis (Latreille, 1796)].

Author and article information

Journal

Affiliations

Author notes

Article

History

Categories

Comments

Comment on this article

Similar content 371

Cited by 12

Most referenced authors 103