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Pragmatic staging of oesophageal cancer using decision theory involving selective endoscopic ultrasonography, PET and laparoscopy.

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      Abstract

      Following CT, guidelines for staging oesophageal and gastro-oesophageal junction (GOJ) cancer recommend endoscopic ultrasonography (EUS), PET-CT and laparoscopy for T3-T4 GOJ tumours. These recommendations are based on generic utilities, but it is unclear whether the test risk outweighs the potential benefit for some patients. This study sought to quantify investigation risks, benefits and utilities, in order to develop pragmatic, personalized staging recommendations.

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      Affiliations
      [1 ] Oxford OesophagoGastric Centre, Oxford, UK.
      [2 ] National Institute for Health Research Oxford Biomedical Research Centre, Oxford, UK.
      [3 ] Department of Radiology, Churchill Hospital, Oxford, UK.
      [4 ] Department of Gastroenterology, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
      [5 ] Department of Oncology, University of Oxford, Oxford, UK.
      Journal
      Br J Surg
      The British journal of surgery
      Wiley-Blackwell
      1365-2168
      0007-1323
      Nov 2015
      : 102
      : 12
      26458070 10.1002/bjs.9905

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