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      Placebo-controlled, double-blind clinical trial of alprenolol in African hypertensive patients.

      , ,
      Current medical research and opinion
      Informa Healthcare

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          Abstract

          A placebo-controlled, double-blind clinical trial of alprenolol was carried out in 20 hypertensive Africans. The active drug and placebo were each administered for 8 weeks using a crossover design. Alprenolol was given in the form of a slow-release tablet preparation at a dosage of 200 mg twice daily. Four patients were withdrawn from the study either because of side-effects (2 patients) or non-compliance (2 patients). The mean reduction in blood pressure obtained in the 16 patients who completed the trial was less than that usually reported in Caucasians.

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          Author and article information

          Journal
          Curr Med Res Opin
          Current medical research and opinion
          Informa Healthcare
          0300-7995
          0300-7995
          1979
          : 6
          : 5
          Article
          10.1185/03007997909109451
          396111
          0ffcc241-a6fa-45a9-96a4-09da8474b4ec
          History

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