Serum tumor necrosis factor in patients with gastric cancer.

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Abstract

We have measured serum TNF-alpha levels in 220 gastric cancer patients, 9 patients with gastric polyps or ulcers, 9 hepatitis B carriers and 85 normal controls. The results showed that no positive TNF-alpha value (> 10 pg/ml) was detected in Hepatitis B carriers and benign gastric lesions' patients and normal controls. In the cancer group, 17 out of 220 patients (7.7%) had positive-TNF-alpha values. The proportion of TNF-alpha positive was 6.8% in stage I disease, 6.5% in stage II disease, 3.7% stage III, and 12.9% stage IV. No clinicopathologic factors were related to positive TNF-alpha value. TNF-alpha value was not an independent prognostic indicator The role of TNF-alpha in gastric cancer remains obscures.

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Journal

Journal ID (iso-abbrev): Anticancer Res.

Title: Anticancer research

ISSN: 0250-7005

ISSN (Print): 0250-7005

Publication date (Electronic): July 23 1998

Volume: 18

Issue: 3A

Affiliations

[1 ] Department of Surgery, Veterans General Hospital-Taipei, Taiwan, Republic of China. cwwu@ics1.vghtpe.gov.tw

Article

PubMed ID: 9673376

SO-VID: 10138f8b-a989-4da5-ba38-e380749d50e7

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