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      Comparative Assessment of the Different American College of Rheumatology/European League Against Rheumatism Remission Definitions for Rheumatoid Arthritis for Their Use as Clinical Trial End Points.

      1 , 2 , 3
      Arthritis & rheumatology (Hoboken, N.J.)
      Wiley

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          Abstract

          The American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) have defined remission using Boolean- or index-based criteria (i.e., a Simplified Disease Activity Index [SDAI] score of ≤3.3). We undertook this study to compare definitions of remission to inform choice of end points for future rheumatoid arthritis (RA) clinical trials, and we also included in our comparison the remission criterion of a score of ≤2.8 on the Clinical Disease Activity Index (CDAI).

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          Author and article information

          Journal
          Arthritis & rheumatology (Hoboken, N.J.)
          Wiley
          2326-5205
          2326-5191
          March 2017
          : 69
          : 3
          Affiliations
          [1 ] Janssen Research & Development, Havertown, Pennsylvania (retired).
          [2 ] Janssen Research & Development, Spring House, Pennsylvania, and University of Pennsylvania Hospital, Philadelphia.
          [3 ] Medical University of Vienna, Vienna, Austria.
          Article
          10.1002/art.39945
          27696724
          10b4d956-bb7c-457a-955f-643a0c92b9c1

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