4
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Caspase inhibitors attenuate oxyhemoglobin-induced apoptosis in endothelial cells.

      1 , , ,
      Stroke

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Our recent study showed that oxyhemoglobin (OxyHb) induces apoptosis in cultured endothelial cells. Apoptosis requires the action of various classes of proteases, including a family of cysteine proteases known collectively as the caspases. This study was undertaken to investigate the effect of 2 caspase inhibitors, Z-VDVAD-FMK and Z-DEVD-FMK, in the protection of endothelial cells from OxyHb-induced apoptosis.

          Related collections

          Author and article information

          Journal
          Stroke
          Stroke
          1524-4628
          0039-2499
          Feb 2001
          : 32
          : 2
          Affiliations
          [1 ] Department of Neurosurgery, University of Mississippi Medical Center, Jackson 39216, USA.
          Article
          10.1161/01.str.32.2.561
          11157197
          10ebfcd2-a2d2-45ec-98ea-e821ffe79152
          History

          Comments

          Comment on this article