Diagnosis of Schistosoma haematobium infection with a mobile phone-mounted Foldscope and a reversed-lens CellScope in Ghana.

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Abstract

We evaluated two novel, portable microscopes and locally acquired, single-ply, paper towels as filter paper for the diagnosis of Schistosoma haematobium infection. The mobile phone-mounted Foldscope and reversed-lens CellScope had sensitivities of 55.9% and 67.6%, and specificities of 93.3% and 100.0%, respectively, compared with conventional light microscopy for diagnosing S. haematobium infection. With conventional light microscopy, urine filtration using single-ply paper towels as filter paper showed a sensitivity of 67.6% and specificity of 80.0% compared with centrifugation for the diagnosis of S. haematobium infection. With future improvements to diagnostic sensitivity, newer generation handheld and mobile phone microscopes may be valuable tools for global health applications.

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Author and article information

Journal

Journal ID (iso-abbrev): Am. J. Trop. Med. Hyg.

Title: The American journal of tropical medicine and hygiene

Publisher: American Society of Tropical Medicine and Hygiene

ISSN (Electronic): 1476-1645

ISSN (Print): 0002-9637

Publication date (Electronic): Jun 2015

Volume: 92

Issue: 6

Affiliations

[1 ] Division of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana; Department of Mechanical Engineering, Stanford University, Stanford, California; Department of Bioengineering, Stanford University, Stanford, California; Department of Bioengineering, University of California, Berkeley, Berkeley, California; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Divisions of Internal Medicine and Infectious Diseases, University Health Network, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

[2 ] Division of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana; Department of Mechanical Engineering, Stanford University, Stanford, California; Department of Bioengineering, Stanford University, Stanford, California; Department of Bioengineering, University of California, Berkeley, Berkeley, California; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Divisions of Internal Medicine and Infectious Diseases, University Health Network, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada isaac.bogoch@uhn.ca.

Article

Publisher Item ID: ajtmh.14-0741

DOI: 10.4269/ajtmh.14-0741

PMC ID: 4458833

PubMed ID: 25918211

SO-VID: 10fdb009-6ed2-4b40-8661-42c7039511cb

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