Chun-Chia Cheng:
ORCID: http://orcid.org/0000-0002-6455-1798
Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – original draft
Jungshan Chang: Role: Conceptualization
Stanley Ching-Cheng Huang: Role: Writing – review & editing
Huan-Chau Lin: Role: Funding acquisition
Ai-Sheng Ho: Role: ConceptualizationRole: Funding acquisition
Ken-Hong Lim: Role: ConceptualizationRole: Supervision
Chun-Chao Chang: Role: ConceptualizationRole: Data curationRole: Resources
Ling Huang: Role: Writing – review & editing
Yu-Cheng Chang: Role: Validation
Yi-Fang Chang: Role: ConceptualizationRole: Project administrationRole: SupervisionRole: Writing
– review & editing
Cheng-Wen Wu: Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
SupervisionRole: Writing – review & editing
Jung Weon Lee: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
7
August
2017
Publication date Collection: 2017
Volume: 12
Issue: 8
Electronic Location Identifier: e0182149
Affiliations
[1
]
Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial
Hospital, Taipei, Taiwan
[2
]
Laboratory of Good Clinical Research Center, Department of Medical Research, MacKay
Memorial Hospital, Tamsui District, New Taipei City, Taiwan
[3
]
Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
[4
]
Graduate Institute of Medical Sciences, School of Medicine, College of Medicine, Taipei
Medical University, Taipei, Taiwan
[5
]
Department of Pathology & Immunology, Washington University School of Medicine, St.
Louis, Missouri, United States of America
[6
]
Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, Taiwan
[7
]
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei
Medical University Hospital, Taipei, Taiwan
[8
]
Division of Gastroenterology and Hepatology, Department of Internal Medicine, School
of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Seoul National University College of Pharmacy, REPUBLIC OF KOREA
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-17-04178
DOI: 10.1371/journal.pone.0182149
PMC ID: 5546577
PubMed ID: 28787001
SO-VID: 11508b14-d699-49eb-aa2a-d0ed6ec8b91d
Copyright © © 2017 Cheng et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
This study was supported by grants from the Ministry of Science and Technology of
Taiwan (MOST 105-2811-B-010-001), Cheng Hsin General Hospital (104-03), and Mackay
Memorial Hospital (MMH-CT-10501).
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Lung and Intrathoracic Tumors
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Post-Translational Modification
Subject:
Phosphorylation
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancer Treatment
Subject:
Research and Analysis Methods
Subject:
Chemical Synthesis
Subject:
Reductive Methylation
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Reactions
Subject:
Methylation
Subject:
Biology and life sciences
Subject:
Cell biology
Subject:
Chromosome biology
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Lung and Intrathoracic Tumors
Subject:
Secondary Lung Tumors
